The Heart-Forming Areas of the Early Chick Blastoderm
The Heart-Forming Areas of the Early Chick Blastoderm
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早期鸡胚层的心脏形成区域
DOI：
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发表时间：
1943
期刊：
影响因子：
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通讯作者：
M. E. Rawles
中科院分区：
文献类型：
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作者：
M. E. Rawles
在早期的一系列实验中（Rawles，1936），通过测试绒膜-尿囊膜上的早期鸡胚盘（头突阶段）的小测量块的发育能力，证明了特定的器官组织从相当确定的区域发育;也就是说，器官形成区域在很大程度上是局部的。因此，某些特定水平的器官区域具有特征性，以至于发现可以沿前后轴指定沿着眼形成水平、甲状腺形成水平、中肾形成水平等。除了与前后轴的这种关系外，还发现许多器官与中外侧组织有明确的关系。例如，发现心脏和肝脏仅在外侧区域发育;其他器官组织，如腱索和肾上腺，仅在中间区域发育，而许多器官组织，如眼睛，耳朵和中肾，在中间和外侧区域都发育，但在中间区域发育。
I N AN earlier series of experiments (Rawles, 1936) it was demonstrated, by testing the developmental potencies of small measured pieces of the early chick blastoderm (head-process stage) on the chorio-allantoic membrane, that particular organ tissues develop from rather definite regions; that is to say, organforming areas are localized to a remarkable extent. So characteristic are some organ areas of particular levels that it was found possible to designate along the anteroposterior axis an eye-forming level, a thyroid-forming level, a mesonephros-forming level, etc. In addition to this relation to anteroposterior axiation many organs were found to show a definite relation to mediolateral organization. Heart and liver, for example, were found to develop in lateral areas only; other organ tissues, like chorda and suprarenal, in median areas only, while many-like eye, ear, and mesonephros-developed in both median and lateral areas but with a