A polytene chromosome analysis of the Anopheles gambiae species complex
A polytene chromosome analysis of the Anopheles gambiae species complex
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DOI：
10.1126/science.1077769
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发表时间：
2002-11-15
期刊：
影响因子：
56.9
通讯作者：
Petrarca, V
中科院分区：
文献类型：
--
作者：
Coluzzi, M;Sabatini, A;Petrarca, V
在冈比亚按蚊复合体的所有已知类群的现场采集标本进行了分析的染色体倒位的基础上，参考一个标准的多线染色体图谱。从固定倒位的分布可以推断出该复合体中7个种之间的系统发育关系。观察到倒位分布的非随机模式，特别是在染色体臂2R上，为A. gambiae、A. arabiensis和A.美拉丝以. gambiae从马里，稳定的遗传分化，甚至在生活在同一地区的人群中观察到，这表明一个过程的初期形态，这是正在证实的研究与分子标记。染色体的分化在中华绒螯蟹物种形成中的可能作用。冈比亚复合体和在出现不同的染色体形式内的名义物种的讨论与人类疟疾。
Field-collected specimens of all known taxa in the Anopheles gambiae complex were analyzed on the basis of chromosome inversions with reference to a standard polytene chromosome map. The phylogenetic relationships among the seven described species in the complex could be inferred from the distribution of fixed inversions. Nonrandom patterns of inversion distribution were observed and, particularly on chromosome arm 2R, provided evidence for genetically distinct populations in A. gambiae, A. arabiensis, and A. melas. In A. gambiae from Mali, stable genetic differentiation was observed even in populations living in the same region, suggesting a process of incipient speciation which is being confirmed by studies with molecular markers. The possible role of chromosome differentiation in speciation of the A. gambiae complex and in the emergence of distinct chromosomal forms within the nominal species is discussed in relation to human malaria.