Recent trends in colorectal cancer mortality in Europe
Recent trends in colorectal cancer mortality in Europe
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DOI：
10.1002/ijc.25653
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发表时间：
2011-07-01
影响因子：
6.4
通讯作者：
La Vecchia, Carlo
中科院分区：
文献类型：
--
作者：
Bosetti, Cristina;Levi, Fabio;La Vecchia, Carlo
在过去的20年里，欧洲的结直肠癌死亡率一直在下降，特别是在女性中，然而，不同国家和年龄段的趋势是不同的。我们使用世界卫生组织(WHO)的数据更新了2007年欧洲结直肠癌死亡率趋势。分析了整个人口的比率，并分别在年轻、中年和老年人口中进行了分析。在欧洲联盟(欧盟)，1997年至2007年期间，结直肠癌死亡率每年下降约2%，从19.7/10万男性降至17.4/10万男性(世界标准死亡率)，从12.5/10万女性降至10.5/10万女性。西欧和北欧国家出现了持续的有利趋势，而包括捷克共和国、匈牙利和斯洛伐克在内的几个东欧国家最近出现了下降，特别是妇女(但罗马尼亚和俄罗斯联邦除外)。2007年，斯洛伐克、匈牙利、克罗地亚、捷克共和国和斯洛文尼亚的男性结直肠癌死亡率(超过25/100,000)和匈牙利、挪威、丹麦和斯洛伐克的女性(超过14/100,000)的结直肠癌死亡率仍然很高。大多数欧洲国家的年轻人(30-49岁)的结直肠癌死亡率趋势更为有利，自20世纪90年代初以来，欧盟男性和女性的结直肠癌死亡率每年下降约2%。最近几个欧洲国家结直肠癌死亡率的下降可能是由于(早期)诊断和治疗的改善，从而提高了这种疾病的存活率。然而，进一步减轻结直肠癌负担的干预措施仍然是有必要的，特别是在东欧国家。
Colorectal cancer mortality has been declining over the last two decades in Europe, particularly in women, the trends being, however, different across countries and age groups. We updated to 2007 colorectal cancer mortality trends in Europe using data from the World Health Organization (WHO). Rates were analyzed for the overall population and separately in young, middle-age and elderly populations. In the European Union (EU), between 1997 and 2007 mortality from colorectal cancer declined by around 2% per year, from 19.7 to 17.4/100,000 men (world standardized rates) and from 12.5 to 10.5/100,000 women. Persisting favorable trends were observed in countries of western and northern Europe, while there were more recent declines in several countries of eastern Europe, including the Czech Republic, Hungary and Slovakia particularly in women (but not Romania and the Russian Federation). In 2007, a substantial excess in colorectal cancer mortality was still observed in Slovakia, Hungary, Croatia, the Czech Republic and Slovenia in men (rates over 25/100,000), and in Hungary, Norway, Denmark and Slovakia in women (rates over 14/100,000). Colorectal mortality trends were more favorable in the young (30-49 years) from most European countries, with a decline of similar to 2% per year since the early 1990s in both men and women from the EU. The recent decreases in colorectal mortality rates in several European countries are likely due to improvements in (early) diagnosis and treatment, with a consequent higher survival from the disease. Interventions to further reduce colorectal cancer burden are, however, still warranted, particularly in eastern European countries.