Management of Attention-Deficit Disorder and Attention-Deficit/Hyperactivity Disorder Drug Intoxication in Dogs and Cats

Management of Attention-Deficit Disorder and Attention-Deficit/Hyperactivity Disorder Drug Intoxication in Dogs and Cats
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DOI:
10.1016/j.cvsm.2012.01.004
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发表时间:
2012-03-01
影响因子:
1.9
通讯作者:
Schell, Mary
Schell, Mary
中科院分区:
农林科学2区
文献类型:
--
作者:
Stern, Laura A.;Schell, Mary

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通常用于治疗人类注意力缺陷/多动障碍或注意力缺陷障碍的药物有两种:安非他明或类似兴奋剂和非安非他明托莫西汀。我们描述了安非他明和类似药物以及托莫西汀对狗和猫的毒性和治疗。安非他明中毒可引起危及生命的刺激症状。治疗的目的是防止吸收、控制刺激信号和保护肾脏;预后一般良好。托莫西汀起效快;经常出现多动和心动过速等刺激症状。关于阿托莫西汀对猫和狗毒性的治疗的公开数据很少。
Two types of drugs are generally used for treating attention-deficit/hyperactivity disorder or attention-deficit disorder in humans: amphetamines or similar stimulants and the nonamphetamine atomoxetine. We describe the toxicity and treatment of both amphetamines and similar medications and atomoxetine in dogs and cats. Amphetamine intoxication can cause life-threatening stimulatory signs. Treatment is aimed at preventing absorption, controlling the stimulatory signs, and protecting the kidneys; prognosis is generally good. Atomoxetine also has a fast onset of action; stimulatory signs such as hyperactivity and tachycardia are often seen. There are little published data about treatment of atomoxetine toxicity in cats and dogs.