A practical kinetic resolution of 4-acetyl[2.2]paracyclophane
A practical kinetic resolution of 4-acetyl[2.2]paracyclophane
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DOI:
10.1016/s0957-4166(01)00452-9
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发表时间:
2001-10-15
影响因子:
--
通讯作者:
Kagan, HB
中科院分区:
文献类型:
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作者:
Dorizon, P;Martin, C;Kagan, HB
The kinetic resolution of 4-acetyl[2.2]paracyclophane has been realized by borane reduction in the presence of a CBS catalyst. The structure of the two diastereomeric alcohol products has been established, The ketone was recovered in more than 99% e.e. at 69% conversion. (C) 2001 Elsevier Science Ltd. All rights reserved.