TREATMENT OF ADVANCED OVARIAN-CANCER WITH POLYINOSINIC POLYCYTIDYLIC LYSINE CARBOXYMETHYLCELLULOSE (POLY(ICLC))
TREATMENT OF ADVANCED OVARIAN-CANCER WITH POLYINOSINIC POLYCYTIDYLIC LYSINE CARBOXYMETHYLCELLULOSE (POLY(ICLC))
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DOI：
10.1016/0090-8258(86)90313-6
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发表时间：
1986-07-01
影响因子：
4.7
通讯作者：
DISAIA, PJ
中科院分区：
文献类型：
--
作者：
RETTENMAIER, MA;BERMAN, ML;DISAIA, PJ
本文报告用聚肌胞羧甲基纤维素（poly（ICLC））治疗晚期卵巢癌8例。毒性很大。在这一小群患者中未观察到任何反应。在晚期卵巢癌患者中使用所述剂量的聚（ICLC）的进一步临床试验似乎没有必要。
Eight patients with advanced ovarian cancer were treated with polyinosinic-polycytidylic lysine carboxymethylcellulose (poly(ICLC)). Toxicity was substantial. No responses were seen in this small group of patients. Further clinical trials utilizing poly(ICLC) at the doses described in patients with advanced ovarian cancer do not appear to be warranted.