[Endemic hepatitis B in 2 marginal ethnic minorities. Comparative study].
[Endemic hepatitis B in 2 marginal ethnic minorities. Comparative study].
复制标题
[2个边缘少数民族流行乙型肝炎。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
J. Zubicoa Ventura
中科院分区：
文献类型：
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作者：
M. T. Virto Ruiz;M. Marín Alcalá;T. Pascual Val;C. López Morrás;I. Aramburu Bergua;J. Zubicoa Ventura
背景
了解并比较B型肝炎（HB）在两个边缘人群（雪茄人和吉普赛人）中的患病率，这两个边缘人群可能属于同一种族群体，并被认为具有较高的疾病风险。
方法
在245支雪茄（占总雪茄人口的65%）和127名吉普赛人（占总吉普赛人口的45%）中测定了血清学标记物。从附近随机选择的103个人作为对照组进行了研究。
结果
HBsAg在吉普赛人中为阴性，在对照组中为0.9%，在香烟组中为27%（p < 0.001）。HBeAg在吸烟组中阳性率为15%，而在其他两组中均为阴性（P < 0.001）。在10%的对照组、12%的吉普赛人和72%的香烟组中发现了抗体（p < 0.001）。在吉普赛人中，发现29%的人从青春期开始感染，而对照组为13%（p < 0.001）。高家庭内的水平传播在婴儿期被发现在雪茄除了垂直传播。
结论
雪茄人与吉普赛人的不同生活习惯和更不稳定的生活方式可能是前者出现B型肝炎高血症的原因。
BACKGROUND
To know and compare the prevalence of hepatitis B (HB) in two marginal populations (ciganes and gypsies) presumably pertaining to the same ethnic group and considered to have high risk for the disease.
METHODS
Serologic markers were determined in 245 ciganes (65% of the total of the cigane population) and in 127 gypsies (45% of the total gypsy population). One hundred three individuals randomly chosen from the neighborhood were studied as a control group.
RESULTS
HbsAg was negative in the gypsies and positive in 0.9% of the controls and in 27% of the ciganes (p < 0.001). HbeAg was positive in 15% of the ciganes and negative in the other two groups (p < 0.001). Antibodies were found in 10% of the controls, 12% of the gypsies and in 72% of the ciganes (p < 0.001). In gypsies it was found that 29% were infected from adolescence versus 13% of the control population (p < 0.001). High intrafamily horizontal transmission in infancy was found in the ciganes in addition to vertical transmission.
CONCLUSIONS
The different habits and more precarious life style of the ciganes with respect to the gypsies may be the cause for the hyperendemia of hepatitis B in the former.