Effectiveness of Collaborative Care for Depression in Human Immunodeficiency Virus Clinics
Effectiveness of Collaborative Care for Depression in Human Immunodeficiency Virus Clinics
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DOI：
10.1001/archinternmed.2010.395
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发表时间：
2011-01-10
影响因子：
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通讯作者：
Gifford, Allen L.
中科院分区：
文献类型：
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作者：
Pyne, Jeffrey M.;Fortney, John C.;Gifford, Allen L.
背景：抑郁症在人类免疫缺陷病毒 (HIV) 感染者中很常见，并且与不良后果相关。方法：在 3 个退伍军人事务部 HIV 诊所进行的单盲随机对照有效性试验（HIV 将抑郁症转化为有效解决方案 [HITIDES]）。 HITIDES 干预措施由一个异地 HIV 抑郁症护理团队（注册护士抑郁症护理经理、药剂师和精神科医生）组成，该团队在基于网络的决策支持系统的支持下提供长达 12 个月的协作护理。 Participants who completed the baseline telephone interview were 249 HIV-infected patients with depression, of whom 123 were randomized to the intervention and 126 to usual care.参与者访谈数据是在基线以及 6 个月和 12 个月的随访时收集的。主要结局是使用 20 项霍普金斯症状检查表 (SCL-20) 测量抑郁严重程度，并报告为治疗反应（SCL-20 项目评分下降 >= 50%）、缓解（平均 SCL-20 项目评分、
Background: Depression is common among persons with the human immunodeficiency virus (HIV) and is associated with unfavorable outcomes.Methods: A single-blind randomized controlled effectiveness trial at 3 Veterans Affairs HIV clinics (HIV Translating Initiatives for Depression Into Effective Solutions [HITIDES]). The HITIDES intervention consisted of an off-site HIV depression care team (a registered nurse depression care manager, pharmacist, and psychiatrist) that delivered up to 12 months of collaborative care backed by a Web-based decision support system. Participants who completed the baseline telephone interview were 249 HIV-infected patients with depression, of whom 123 were randomized to the intervention and 126 to usual care. Participant interview data were collected at baseline and at the 6- and 12-month follow-up visits. The primary outcome was depression severity measured using the 20-item Hopkins Symptom Checklist (SCL-20) and reported as treatment response (>= 50% decrease in SCL-20 item score), remission (mean SCL-20 item score,