Individual radiation therapy patient whole-body phantoms for peripheral dose evaluations: method and specific software
Individual radiation therapy patient whole-body phantoms for peripheral dose evaluations: method and specific software
复制标题
DOI：
10.1088/0031-9155/54/17/n01
复制
发表时间：
2009-09-07
影响因子：
3.5
通讯作者：
Diallo, I.
中科院分区：
文献类型：
--
作者：
Alziar, I.;Bonniaud, G.;Diallo, I.
这项研究提出了一种方法，旨在创建放射治疗(RT)患者可调整的全身模型，以允许进行回顾性和前瞻性的外围剂量评估，以增强患者的辐射防护。我们的策略包括针对不同性别和不同年龄段的不同放射治疗姿势的虚拟全身患者模型(WBPM)。它包括一个软件工具，旨在根据可用的患者数据质量，将幻影的解剖结构与实际患者的解剖结构相匹配。调整WBPM以适应患者形态的程序包括法国人群基本营养学表格中提供的典型尺寸。调整是半自动的。由于人体解剖学的复杂性，需要熟练的人员来验证在体模解剖学中所做的改变。这项研究是一个全球性项目的一部分，该项目旨在提出适当的方法和软件工具，能够在适应的治疗计划系统(TPS)中重建RT患者全身的解剖和剂量评估。图形用户界面是适于获得舒适工作过程的TPS的图形用户界面。这种WBPM已被用于补充患者治疗计划图像，通常限于参与治疗的区域。在这里，我们报告一个例子，一个前列腺癌患者的治疗计划图像与一个解剖模型相辅相成。尽管目前的结果是初步的，我们的研究仍在进行中，但它们似乎令人鼓舞，因为这种患者调整的模体对于优化患者的辐射防护和后续研究至关重要。
This study presents a method aimed at creating radiotherapy (RT) patient-adjustable whole-body phantoms to permit retrospective and prospective peripheral dose evaluations for enhanced patient radioprotection. Our strategy involves virtual whole-body patient models (WBPM) in different RT treatment positions for both genders and for different age groups. It includes a software tool designed to match the anatomy of the phantoms with the anatomy of the actual patients, based on the quality of patient data available. The procedure for adjusting a WBPM to patient morphology includes typical dimensions available in basic auxological tables for the French population. Adjustment is semi-automatic. Because of the complexity of the human anatomy, skilled personnel are required to validate changes made in the phantom anatomy. This research is part of a global project aimed at proposing appropriate methods and software tools capable of reconstituting the anatomy and dose evaluations in the entire body of RT patients in an adapted treatment planning system (TPS). The graphic user interface is that of a TPS adapted to obtain a comfortable working process. Such WBPM have been used to supplement patient therapy planning images, usually restricted to regions involved in treatment. Here we report, as an example, the case of a patient treated for prostate cancer whose therapy planning images were complemented by an anatomy model. Although present results are preliminary and our research is ongoing, they appear encouraging, since such patient-adjusted phantoms are crucial in the optimization of radiation protection of patients and for follow-up studies.