Elastic properties and strength of a novel small-diameter, compliant polyurethane vascular graft.

Elastic properties and strength of a novel small-diameter, compliant polyurethane vascular graft.
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新型小直径、顺应性聚氨酯血管移植物的弹性和强度。

DOI:
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发表时间:
1989
期刊:
Journal of Biomedical Materials Research
影响因子:
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通讯作者:
K. Kondo
K. Kondo
中科院分区:
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文献类型:
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作者:
K. Hayashi;K. Takamizawa;T. Saito;K. Kira;K. Hiramatsu;K. Kondo

文献摘要

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测定了一种新开发的小直径动脉移植物的拉伸性能和压力-直径-轴向力关系,并与市售移植物和天然动脉进行了比较。该材料由4,4 '-二苯基甲烷二异氰酸酯、聚四亚甲基二醇和聚环氧乙烷合成,用乙二醇扩链。多孔导管(3-mm内径)由该材料通过相分离技术制造,并且它们的外表面用羊毛状聚酯网覆盖以防止过度扩张。力学测试表明,聚氨酯移植物具有与天然动脉相似的扩张性和强度,已被证明可用于动脉重建,特别是用于小直径血管的替代。
Tensile properties and pressure-diameter-axial force relations of a newly developed small-diameter arterial graft were determined and compared to those of commercially available grafts and natural arteries. The material was synthesized from 4,4'-diphenylmethane diisocyanate, polytetramethylene glycol, and polyethylene oxide, chain-extended with ethylene glycol. Porous conduits (3-mm internal diameter) were fabricated of this material by means of a phase separation technique, and their outer surfaces were covered with woolly polyester net in order to prevent excessive dilation. Mechanical tests indicated that the polyurethane graft has distensibility and strength similar to that of natural arteries, and has been proved to be useful for the arterial reconstruction, particularly for the replacement of small-diameter blood vessels.