Impact of improved survival of very low birth weight infants on recent secular trends in the prevalence of cerebral palsy.
Impact of improved survival of very low birth weight infants on recent secular trends in the prevalence of cerebral palsy.
复制标题
极低出生体重婴儿生存率的提高对近期脑瘫患病率长期趋势的影响。
DOI：
10.1542/peds.91.6.1094
复制
发表时间：
1993
期刊：
影响因子：
8
通讯作者：
John L. Kiely
中科院分区：
文献类型：
--
作者：
V. Bhushan;Nigel Paneth;John L. Kiely
客观化
回顾在工业化国家中脑瘫患病率的最新长期趋势，这些国家有基于人口的脑瘫登记，并估计美国的这种时间趋势，直到最近，美国还没有这样的登记。
数据源
最近在同行评议的英文期刊上发表的脑瘫流行病学研究，以及与脑瘫的主要人口统计学决定因素有关的美国重要数据--出生率、出生体重分布、出生体重相关的死亡风险以及幸存者中的脑瘫风险。
结果
工业化国家的大多数流行病学研究表明，近几十年来，儿童脑瘫的患病率有所上升，这主要是因为低出生体重和极低出生体重的儿童对脑瘫患病率的贡献越来越大。在美国，脑瘫患病率正在迅速变化的唯一人口统计学决定因素是低出生体重和极低出生体重婴儿的存活率。根据低出生体重儿和极低出生体重儿存活率的变化幅度，据估计，1960年至1986年间，美国儿童脑瘫的患病率上升了约20%。
结论
新生儿重症监护日益成功的一个明显不可避免的副作用是，儿童脑瘫患病率适度上升。
OBJECTIVE
To review recent secular trends in the prevalence of cerebral palsy in industrialized countries that have population-based cerebral palsy registries and to estimate such time-trends for the United States, where until recently such registries were absent.
DATA SOURCES
Recent epidemiologic studies of cerebral palsy published in peer-reviewed journals in English, and US vital data bearing on the principal demographic determinants of cerebral palsy--birth rates, the birth weight distributions, birth weight-specific mortality risk, and cerebral palsy risk among survivors.
RESULTS
Most epidemiologic studies from industrialized countries show a rise in the childhood prevalence of cerebral palsy in recent decades, largely because of the increasing contribution of children of low and very low birth weight to its prevalence. The only demographic determinant of cerebral palsy prevalence that is changing rapidly in the United States is survival of low birth weight and very low birth weight infants. Based on the magnitude of change in the survival of low and very low birth weight infants, it is estimated that childhood prevalence of cerebral palsy rose about 20% between 1960 and 1986 in the United States.
CONCLUSION
An apparently unavoidable side effect of the increasing success of newborn intensive care is a moderate rise in the childhood prevalence of cerebral palsy.