Use of CaH2 as a reductive hydride source:: reduction of ketones and imines with CaH2/ZnX2 in the presence of a Lewis acid

Use of CaH2 as a reductive hydride source:: reduction of ketones and imines with CaH2/ZnX2 in the presence of a Lewis acid
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DOI:
10.1016/j.tetlet.2005.01.058
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发表时间:
2005-03-07
影响因子:
1.8
通讯作者:
Okamoto, S
Okamoto, S
中科院分区:
化学4区
文献类型:
--
作者:
Aida, T;Kuboki, N;Okamoto, S

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在催化量的刘易斯酸如Ti(O-i-Pr)(4)、Al(O-i-Pr)(3)、B(O-i-Pr)(3)和ZnF_2存在下,一种新的复合试剂CaH_2/ZnX_2有效地将各种酮和亚胺分别还原为相应的醇和胺。(C)2005年由Elsevier Ltd.出版
A new combination reagent of CaH2/ZnX2, effectively reduced a variety of ketones and imines to the corresponding alcohols and amines, respectively, in the presence of a catalytic amount of a Lewis acid such as Ti(O-i-Pr)(4), Al(O-i-Pr)(3), B(O-i-Pr)(3) and ZnF2. (C) 2005 Published by Elsevier Ltd.