A case of monocular blindness as the initial presentation of hepatocellular carcinoma with skull metastasis
A case of monocular blindness as the initial presentation of hepatocellular carcinoma with skull metastasis
复制标题
肝细胞癌颅骨转移首发单眼失明一例
DOI：
10.1007/s12328-011-0237-6
复制
发表时间：
2011
期刊：
影响因子：
--
通讯作者：
et al
中科院分区：
文献类型：
--
作者：
Ito J;Okumoto K;Togashi H (15名中14番目);et al
一位52岁的男性患有单眼失明，只有光感，被收入我院。症状开始为低视力，并在3周内迅速发展为右眼单眼失明，无其他全身表现。影像学检查发现多发性肝细胞癌在肝硬化，肿瘤在颅底和脊椎。经鼻内镜肿瘤活检和椎板切除术获得的标本的病理和免疫化学研究显示，他们是转移性肝细胞癌（HCC）。虽然患者接受了放射治疗和化疗，但他在入院后5个月死亡。颅侧肝癌仅累及视神经管，可能优先累及视神经而非其他颅神经。这是第一个报告的肝癌患者单眼失明作为最初的表现。
A 52-year-old man suffering from monocular blindness, with light perception only, was admitted to our hospital. The symptom had begun as low vision and developed rapidly within 3 weeks into monocular blindness in the right eye, with no other systemic manifestations. Imaging examinations revealed multiple hepatocellular carcinomas in the cirrhotic liver, and tumors at the skull base and vertebra. A pathological and immunochemical study of specimens obtained by endoscopic transnasal tumor biopsy and laminectomy revealed them to be metastatic hepatocellular carcinomas (HCCs). Although the patient underwent radiation therapy and chemotherapy, he died 5 months after admission to our hospital. The cranial HCC, involving only the optic canal, may have disturbed the optic nerve in preference to the other cranial nerves. This is the first report of a HCC patient with monocular blindness as the initial presentation of the disease.
登录
查看更多内容
复发性转移性肝细胞癌表现为连续的“镜像”脑内血肿
影响因子：
2
作者：
D. Cho;H. Yi;Y. Ko;S. Oh;Seung;S. Paik
通讯作者：
S. Paik
DOI：
10.1097/wno.0b013e31816754e7
发表时间：
2008
期刊：
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
影响因子：
--
作者：
P. Hirunwiwatkul;Suppapong Tirakunwichcha;Piyawadee Meesuaypong;S. Shuangshoti
通讯作者：
S. Shuangshoti
案例10-1999
DOI：
10.1056/nejm199904083401408
发表时间：
1999
期刊：
The New England Journal of Medicine
影响因子：
--
作者：
David C. Harmon;E. Mark;Jean
通讯作者：
Jean
影响因子：
5.1
作者：
TEARE, JP;WHITEHEAD, M;COKER, RJ
通讯作者：
COKER, RJ
肝细胞癌颅内转移一例[J].
DOI：
10.1159/000325689
发表时间：
1995
期刊：
No to shinkei = Brain and nerve
影响因子：
--
作者：
M. Shibukawa;T. Inagawa;Y. Katoh;Y. Tokuda;N. Ohbayashi;Y. Yoshioka
通讯作者：
Y. Yoshioka