PHOSPHOLIPASE-A ACTIVITY OF LYSOSOMES OF RAT MYOCARDIAL TISSUE
PHOSPHOLIPASE-A ACTIVITY OF LYSOSOMES OF RAT MYOCARDIAL TISSUE
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DOI：
10.1021/bi00753a028
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发表时间：
1972-01-01
期刊：
影响因子：
2.9
通讯作者：
WAITE, M
中科院分区：
文献类型：
--
作者：
FRANSON, R;WEGLICKI, W;WAITE, M
Richard Franson, t Moseley Waite, and William Weglicki abstract: Lysosomes were isolated by isopycnic sucrose gradient centrifugation from myocardial tissue of control rats and rats injectedwith Triton WR-1339. As measured by the shiftsin distribution of acid phosphatase,/3-glucuroni-dase, and one of the phospholipases A, three populations of lysosomes were found which hadengorged Triton. A less dense population contained relatively more/3-glucuronidase, whereas a denser population contained relatively more acid phosphatase. The majority of the lysosomes were unaffected by Triton. Based on the observationsmade on rat skeletal muscle (Canónico, P. G., and Bird, J. W. C.(1970), Cytobios 14, 23), it is suggested that four groups of lysosomes of different cellular origin exist in rat myocardial tissues, and that more than one type of lysosome may be derived from the same cell,
