CT-PATHOLOGICAL CORRELATION IN SMALL PERIPHERAL LUNG CANCERS
CT-PATHOLOGICAL CORRELATION IN SMALL PERIPHERAL LUNG CANCERS
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DOI：
10.2214/ajr.149.6.1139
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发表时间：
1987-12-01
影响因子：
5
通讯作者：
FUJITA, M
中科院分区：
文献类型：
--
作者：
KURIYAMA, K;TATEISHI, R;FUJITA, M
为了评价周围型小肺癌的形态学，我们研究了17例患者的18例周围型小肺癌（14例腺癌，2例鳞状细胞癌，1例大细胞癌和1例类癌）的薄层CT图像。手术切除后，标本进行横向切片，大体形态学和组织学与术前薄层CT图像上病变的外观相关联。18例肺癌CT表现为78%的细毛刺，83%的切迹，78%的胸膜回缩，83%的周围血管会聚。此外，在乳头状腺癌的情况下，病变密度不均（78%）和小空洞（67%）。CT显示高分化或中分化乳头状腺癌多见周边绒毛样带。这与病理学研究中观察到的肺泡壁内衬的肿瘤细胞密切相关。薄层CT图像与病理资料的比较表明，肺-肿瘤界面和肿瘤内部纹理的显示，虽然不是恶性病变的特异性，但可以使CT诊断更准确的周围型小肺癌。
To evaluate the morphology of small peripheral lung cancers, we studied thin-section CT images of 18 small peripheral lung cancers (14 adenocarcinomas, two squamous-cell carcinomas, one large-cell carcinoma, and one carcinoid) in 17 patients. After surgical resection, specimens were sliced transversely, and the gross morphology and histology were correlated with the appearance of the lesion on preoperative thin-section CT images. CT images showed fine spiculations in 78%, a notch in 83%, pleural retraction in 78%, and convergence of peripheral vessels in 83% of the 18 lung cancers. Furthermore, in cases of papillary adenocarcinoma, the lesions had heterogeneous densities (78%) and small cavitations (67%). CT showed a peripheral fluffy zone in most of the well- or moderately differentiated papillary adenocarcinomas. This correlated well with tumor cells lining the alveolar walls, observed in pathologic studies. Comparison of thin-section CT images with pathologic data suggests that the demonstration of the lung-tumor interface and the tumor''s internal texture, while not specific for malignant lesions, can make the CT diagnosis of small peripheral lung cancers more accurate.