Can cure be achieved in patients with head and neck carcinomas? The problem of second neoplasm.
Can cure be achieved in patients with head and neck carcinomas? The problem of second neoplasm.
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DOI：
10.1586/14737140.1.1.125
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发表时间：
2001-06-01
影响因子：
3.3
通讯作者：
del Prado Venegas, M
中科院分区：
文献类型：
--
作者：
Leon, X;Quer, M;del Prado Venegas, M
在过去的几十年中，头颈部癌局部控制的改善似乎并没有改变这些患者的最终生存率，这主要是由于远处转移和第二肿瘤的出现。本文就头颈部肿瘤继发肿瘤的发病率、流行病学、对预后的影响、发病机理及预防的可能性等方面进行综述。
The improvement in locoregional control of head and neck carcinomas over the last few decades does not appear to modify the final survival of these patients, mainly due to the appearance of distant metastases and second neoplasms. This article reviews the topic of second neoplasm in patients with an index tumor in the head and neck, making a special point of the incidence and epidemiology of second neoplasms, the influence on prognosis, etiopathogenic theories and the possibility of prevention.