Recent Advances in Electrochemical, Ni‐Catalyzed C−C Bond Formation
Recent Advances in Electrochemical, Ni‐Catalyzed C−C Bond Formation
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DOI：
10.1002/ijch.202300089
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发表时间：
2023-07
影响因子：
3.2
通讯作者：
Mareena C. Franke;D. Weix
中科院分区：
文献类型：
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作者：
Mareena C. Franke;D. Weix
镍催化交叉亲电偶联（XEC）是形成碳碳键的有效方法，已成为构建复杂分子的重要工具。虽然XEC最常使用化学计量的金属还原剂，但这些转化也可以电化学驱动。电化学XEC（eXEC）是一种很有吸引力的方法，因为它可以提高XEC的绿色度，近年来这种潜力已经导致了许多进展。本综述的重点是自2010年以来报道的电化学，Ni催化的碳-碳键形成反应，并按阳极半反应的类型进行分类：牺牲阳极，牺牲还原剂和会聚成对电解。重点介绍了关键的发展，并讨论了需要更多的可扩展的选项。
Nickel‐catalyzed cross‐electrophile coupling (XEC) is an efficient method to form carbon‐carbon bonds and has become an important tool for building complex molecules. While XEC has most often used stoichiometric metal reductants, these transformations can also be driven electrochemically. Electrochemical XEC (eXEC) is attractive because it can increase the greenness of XEC and this potential has resulted in numerous advances in recent years. The focus of this review is on electrochemical, Ni‐catalyzed carbon‐carbon bond forming reactions reported since 2010 and is categorized by the type of anodic half reaction: sacrificial anode, sacrificial reductant, and convergent paired electrolysis. The key developments are highlighted and the need for more scalable options is discussed.