THE PITCH OF CHROMATIN DNA IS REFLECTED IN ITS NUCLEOTIDE-SEQUENCE
THE PITCH OF CHROMATIN DNA IS REFLECTED IN ITS NUCLEOTIDE-SEQUENCE
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DOI：
10.1073/pnas.77.7.3816
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发表时间：
1980-01-01
期刊：
影响因子：
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通讯作者：
SUSSMAN, JL
中科院分区：
文献类型：
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作者：
TRIFONOV, EN;SUSSMAN, JL
染色质DNA核苷酸序列的相关性分析揭示了某些二核苷酸沿序列以3至约10.5个碱基的周期沿着重复的明显趋势。后一个时期，在实验误差范围内与最近对DNA双螺旋螺距的估计相等[（Wang，1979）和Trifonov和Bettecken，（1979）]，被解释为DNA分子的变形各向异性的反映，这有助于其在染色质中的平滑折叠。[研究了病毒和真核生物的DNA。]
A correlation analysis of chromatin DNA nucleotide sequences reveals the clear tendency of some of the dinucleotides to be repeated along the sequences with periods of 3 and about 10.5 bases. This latter period, which is equal within experimental error to recent estimates of the pitch of the DNA double helix [(Wang, 1979) and Trifonov and Bettecken, (1979)] is interpreted as a reflection of the deformational anisotropy of the DNA molecule that facilitates its smooth folding in chromatin. [Viral and eukaryotic DNA were studied.].