Implication of regulatory networks of long noncoding RNA/circular RNA-miRNA-mRNA in diabetic cardiovascular diseases.
Implication of regulatory networks of long noncoding RNA/circular RNA-miRNA-mRNA in diabetic cardiovascular diseases.
复制标题
长链非编码RNA/环状RNA-miRNA-mRNA调控网络在糖尿病心血管疾病中的意义。
DOI:
10.2217/epi-2020-0188
复制
发表时间:
2020-11
期刊:
影响因子:
3.8
通讯作者:
Qian Jinqiao
中科院分区:
文献类型:
--
作者:
Xiong Wei;Yao Mengran;Yang Yuqiao;Qu Yan;Qian Jinqiao
Diabetic cardiovascular diseases (DCVDs) are the most common complications of diabetes mellitus and are considered to be one of the most important threats to global health and an economic burden. Long noncoding RNA (lncRNA), circular RNA (circRNA), and miRNA are a novel group of noncoding RNAs that are involved in the regulation of various pathophysiological processes, including DCVDs. Interestingly, both lncRNA and circRNA can act as competing endogenous RNA of miRNA, thereby regulating the expression of the target mRNA by decoying or sponging the miRNA. In this review, we focus on the mechanistic, pathological and functional roles of lncRNA/circRNA-miRNA-mRNA networks in DCVDs and further discuss the potential implications for early detection, therapeutic intervention and prognostic evaluation.
登录
查看更多内容
DOI:
--
发表时间:
2019
期刊:
Front Cell Dev Biol
影响因子:
--
作者:
Xiao-wen Cheng;Zhen-fei Chen;Yu-feng Wan;qing zhou;yuan wang;huaqing zhu
通讯作者:
huaqing zhu
影响因子:
5.4
作者:
Fang Y;Wang X;Li W;Han J;Jin J;Su F;Zhang J;Huang W;Xiao F;Pan Q;Zou L
通讯作者:
Zou L
影响因子:
3.1
作者:
Zhang Xuan;Cheng Long;Xu Longhe;Zhang Yunliang;Yang Yitian;Fu Qiang;Mi Weidong;Li Hao
通讯作者:
Li Hao
影响因子:
2.6
作者:
Jin, Guoxi;Wang, Qiong;Li, Minglong
通讯作者:
Li, Minglong
DOI:
10.1152/ajpheart.00929.2011
发表时间:
2012-05-01
影响因子:
4.8
作者:
Qian, Jinqiao;Ling, Shukuan;Ye, Yumei
通讯作者:
Ye, Yumei