Efficacy of an expanded ventilator bundle for the reduction of ventilator-associated pneumonia in the medical intensive care unit

Efficacy of an expanded ventilator bundle for the reduction of ventilator-associated pneumonia in the medical intensive care unit
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DOI:
10.1016/j.ajic.2008.05.010
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发表时间:
2009-03-01
影响因子:
4.9
通讯作者:
DeBari, Vincent A.
DeBari, Vincent A.
中科院分区:
医学3区
文献类型:
--
作者:
Blamoun, John;Alfakir, Maria;DeBari, Vincent A.

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呼吸机束 (VB) 包括一组临床操作(床头抬高、“镇静假期:”深静脉血栓形成预防和消化性溃疡疾病预防),以改善接受机械通气的患者的预后。我们修改了重症监护病房的标准 VB,纳入一组呼吸治疗师驱动的方案,并且在实施后,观察到呼吸机相关性肺炎 (VAP) 出现统计显着性 (P = .0006) 减少,从中位数 14.1 例/10(3) 呼吸机天数(四分位数范围 [IQR] = 12.1 至 20.6)降至 0 例/10(3)呼吸机天数(IQR = 0 至 1.1)。版权所有 (C) 2009 感染控制和流行病学专业人员协会,Inc.
The ventilator bundle (VB) includes a group of clinical maneuvers (head-of-bed elevation, "sedation vacation:" deep vein thrombosis prophylaxis, and peptic ulcer disease prophylaxis) to improve outcomes in patients undergoing mechanical ventilation. We modified the standard VB in our medical intensive care unit to include a group of respiratory therapist-driven protocols and, post-implementation, observed a statistically significant (P = .0006) reduction in ventilator-associated pneumonia (VAP), from a median of 14.1 cases/10(3) ventilator-days (interquartile range [IQR] = 12.1 to 20.6) to 0 cases/10(3) ventilator-days (IQR = 0 to 1.1). Copyright (C) 2009 Association for Professionals in Infection Control and Epidemiology, Inc.