Screening for neurofibrillary tangles and argyrophilic plaques with Congo Red and polarized light.
Screening for neurofibrillary tangles and argyrophilic plaques with Congo Red and polarized light.
复制标题
使用刚果红和偏振光筛查神经原纤维缠结和嗜银斑块。
DOI：
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发表时间：
1973
影响因子：
3.4
通讯作者：
R. J. T. From
中科院分区：
文献类型：
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作者：
Mollie I. STOKES1;R. J. T. From
银浸渍技术的反复无常使其不适合大量染色和筛查嗜银（老年性）斑块和神经原纤维缠结的切片。为此，我们描述了一种简单，一致和高度敏感的体染色方法。这取决于淀粉样蛋白和斑块和缠结的其他原纤维蛋白成分的亲共性和由此产生的异常颜色或极化（Ladewig, 1945） （Terry and Wisniewski, 1970）。
The capricious nature of silver impregnation techniques renders them unsuitable for bulk staining and screening sections for the presence of argyrophilic (senile) plaques and neurofibrillary tangles. For this purpose, we describe a simple, consistent and highly sensitive bulk staining method. It depends on the congophilia and resultant anomalous colour or polarization (Ladewig, 1945) that characterizes amyloid and other fibrillary protein components of plaques and tangles (Terry and Wisniewski, 1970).