34.4 A 4.5mm3 Deep-Tissue Ultrasonic Implantable Luminescence Oxygen Sensor
34.4 A 4.5mm3 Deep-Tissue Ultrasonic Implantable Luminescence Oxygen Sensor
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34.4 4.5mm3 深层组织超声波植入式发光氧传感器
DOI：
10.1109/isscc19947.2020.9062946
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
M. Maharbiz
中科院分区：
文献类型：
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作者：
S. Sonmezoglu;M. Maharbiz
持续监测局部组织氧合(RTO)可为危重病患者提供治疗指导。目前用于RTO评估的技术需要系留、有线连接或电池，由于其体积大，造成了与植入和长期使用相关的问题。最近，超声(US)已被证明是一种有效的方法，可以无线供电并与组织深处的可植入设备进行通信，使其能够实现微型化[1]，[2]。在这里，我们提出了一个完全植入式，无线，无电池，实时传感器系统，用于深层组织氧(02)监测。该系统将发光传感器与美国技术相结合，实现了与以前演示的任何系统竞争或更好的氧气分辨率、最低的功耗和最小的体积(4.5mm3)[3]-[5]。
Continuous monitoring of regional tissue oxygenation (RTO) can provide therapeutic guidance for critical care patients. Current technologies for RTO assessment require tethered, wired connections or batteries, creating problems related to implantation and chronic use due to their large volume. Recently, ultrasound (US) has been demonstrated as an efficient way to wirelessly power and communicate with implantable devices deep in tissue, enabling their miniaturization [1], [2]. Here, we present a fully implantable, wireless, battery-free, real-time sensor system for deep tissue oxygen (02) monitoring. The system combines a luminescence sensor with US technology, achieving competitive or better O2 resolution, the lowest power consumption and the smallest volume (4.5mm3) of any system previously demonstrated [3]–[5].