Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository
Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository
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DOI：
10.1016/j.urology.2009.05.050
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发表时间：
2010-02-01
期刊：
影响因子：
2.1
通讯作者：
Lin, Daniel W.
中科院分区：
文献类型：
--
作者：
Newcomb, Lisa F.;Brooks, James D.;Lin, Daniel W.
主动监测是针对局限性前列腺癌的管理计划，针对疾病进展的迹象提供选择性延迟干预，使患者能够延迟或避免治疗和相关的副作用。促进积极监测的中心的结果是有利的，疾病特异性生存率高。然而，仍然需要以高特异性区分在监测中进展的侵袭性癌症与惰性癌症的预后变量或生物标志物。金丝雀前列腺主动监测研究是一项多中心研究和生物储存库，将发现和确认由组织学、前列腺特异性抗原或临床标准定义的侵袭性疾病的生物标志物。泌尿学75：407-413，2010年。(C)2010年爱思唯尔公司
Active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance from the indolent cancers. The Canary Prostate Active Surveillance Study is a multicenter study and a biorepository that will discover and confirm biomarkers of aggressive disease as defined by histologic, prostate-specific antigen, or clinical criteria. UROLOGY 75: 407-413, 2010. (C) 2010 Elsevier Inc.