Outcomes of Preterm Infants: Morbidity Replaces Mortality
Outcomes of Preterm Infants: Morbidity Replaces Mortality
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DOI：
10.1016/j.clp.2011.06.011
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发表时间：
2011-09-01
影响因子：
2.1
通讯作者：
Kim, Christina
中科院分区：
文献类型：
--
作者：
Allen, Marilee C.;Cristofalo, Elizabeth A.;Kim, Christina
过去 50 年来，美国早产率不断上升，早产死亡率逐步下降，生存能力极限降低，使早产成为一个重大的公共卫生问题。神经成熟是中枢神经系统 (CNS) 的功能发育，是一个促进和塑造 CNS 结构发育的动态过程。本文回顾了早产结局，认识到多种因素影响神经成熟并导致一系列神经发育障碍、功能障碍和中枢神经系统处理改变。研究了在重症监护室内外保护早产儿并支持其生长发育的方法。
Over the last 50 years in the United States a rising preterm birth rate, a progressive decrease in preterm mortality, and a lowering of the limit of viability have made preterm birth a significant public health problem. Neuromaturation, the functional development of the central nervous system (CNS), is a dynamic process that promotes and shapes CNS structural development. This article reviews preterm outcomes, recognizing that multiple factors influence neuromaturation and lead to a range of neurodevelopmental disabilities, dysfunctions, and altered CNS processing. Ways to protect preterm infants and support their growth and development in and beyond intensive care are examined.