Measuring autistic traits: heritability, reliability and validity of the Social and Communication Disorders Checklist
Measuring autistic traits: heritability, reliability and validity of the Social and Communication Disorders Checklist
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DOI：
10.1192/bjp.187.6.568
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发表时间：
2005-12-01
影响因子：
10.5
通讯作者：
Scourfield, J
中科院分区：
文献类型：
--
作者：
Skuse, DH;Mandy, WPL;Scourfield, J
研究背景孤独症特征在普通人群中广泛分布，但孤独症谱系的界限尚不清楚。由于缺乏合适的筛查工具，对儿童自闭症样本的全人群调查受到阻碍。目的评估社交和沟通障碍量表（SCDC）是否满足对自闭症特征敏感测量的需要，该量表可以在几分钟内完成，并测量男性和女性的遗传特征。方法12项量表，SCDC，完成了三个独立的样本来自双胞胎登记，一组特纳综合征和儿童诊断自闭症谱系障碍参加诊所。结果SCDC测量的各性状在男女两性中均具有高度的遗传力（0.74）。内部一致性良好（0.93），重测信度高（0.81）。广泛性发育障碍与其他临床组的区分效度较好，与非临床组的区分效度较好;敏感度（0.90），特异度（0.69）。结论SCDC是一种独特有效的孤独症特征一级筛查问卷。
Background Autistic traits are widely distributed in the general population, but the boundaries of the autistic spectrum are unclear. Whole-population surveys of unselected samples of children are hampered by the lack of appropriate screening instruments.Aims To assess whether the Social and Communication Disorders Checklist (SCDC) fulfils the need for a sensitive measure of autistic traits, which can be completed in a few minutes and which measures heritable characteristics in both males and females.Method A 12-item scale, the SCDC, was completed by three independent samples drawn from a twin register, a group with Turner syndrome and children with a diagnosis of autistic-spectrum disorder attending clinics. The data were used to establish the heritability reliability and validity of the checklist.Results Traits measured by the SCDC were highly heritable in both genders (0.74). Internal consistency was excellent (0.93) and test-retest reliability high (0.81). Discriminant validity between pervasive developmental disorder and other clinical groups was good, discrimination from non-clinical samples was better; sensitivity (0.90), specificity (0.69).Conclusions The SCDC is a unique and efficient first-level screening questionnaire for autistic traitsDeclaration of interest None.