VASOVAGAL FAINTING - DIPHASIC RESPONSE
VASOVAGAL FAINTING - DIPHASIC RESPONSE
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DOI：
10.1097/00006842-196111000-00004
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发表时间：
1961-01-01
影响因子：
3.3
通讯作者：
LUNSFORD, L
中科院分区：
文献类型：
--
作者：
GRAHAM, DT;KABLER, JD;LUNSFORD, L
在3种不同的情况下研究了血管迷走性（血管抑制性）昏厥：献血者、单纯静脉穿刺者和接受气脑造影术的患者。在第一种情况下观察到10次昏厥，在第二种情况下观察到7次昏厥，在第三种情况下观察到6次昏厥。在所有情况下，以低血压和心动过缓为特征的昏厥本身是双相反应的第二阶段：第一阶段的特征是心率加快或上升，以及血压升高，特别是舒张压。第一阶段（高动力）是焦虑的反映，而第二阶段开始于焦虑的突然停止。这表明，生理上的微弱反映了由第一阶段激活的反射机制的作用，然后突然离开没有反对。昏厥和死亡非常相似，有理由认为某些血管迷走神经性昏厥是致命的。心搏停止在晕厥中并不罕见，通常与抽搐有关。在我们的2名受试者中观察到呼吸暂停。心律紊乱包括A.结性心律、干扰分离和心搏停止（1例持续18秒）观察了4次观察到全身性惊厥，总是与心搏停止相关。
Vasovagal (vasodepressor) fainting was studied in 3 different situations: in persons donating blood, in persons having a simple venipunc-ture, and in patients undergoing pneumoencephalography. Ten faints were observed in the first situation, 7 in the second and 6 in the third. In all instances, the faint itself, characterized by low blood pressure and bradycardia, was the 2d phase of a diphasic response: the 1st phase was characterized by rapid or rising heart rate, and by rising blood pressure, especially diastolic. The 1st (hyperdynamic) phase is a reflection of anxiety, while the 2d phase begins with the sudden cessation of anxiety. It is suggested that physiologically the faint reflects the action of reflex mechanisms activated by the 1st phase, and then left suddenly unopposed. Fainting and dying resemble each other closely, and there is reason to think that some vasovagal faints are fatal. Cardiac asystole is not rare in faints and is often associated with convulsions. Apnea was observed in 2 of our subjects. Disturbances of cardiac rhythm including A. V. nodal rhythm, interference dissociation, and asystole (in 1 instance for 18 sec.) were observed. Generalized convulsions were seen on 4 occasions, always in association with asystole.