Human Mycobacterium bovis infection in ten Latin American countries
Human Mycobacterium bovis infection in ten Latin American countries
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DOI：
10.1016/j.tube.2007.11.007
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发表时间：
2008-07-01
期刊：
影响因子：
3.2
通讯作者：
de Waard, Jacobus H.
中科院分区：
文献类型：
--
作者：
de Kantor, Isabel N.;Ambroggi, Marta;de Waard, Jacobus H.
这项工作的目的是在阿根廷、巴西、智利、哥伦比亚、哥斯达黎加、多米尼加共和国、厄瓜多尔、秘鲁、乌拉圭和委内瑞拉获得牛结核病（BTB）与人类相关性的最佳估计。信息来源是参与实验室填写的调查问卷，以及对已发表文献的检索（1970-2007）。其中只有4个国家报告了经细菌学证实的人类BTB病例。其中大多数是在阿根廷诊断的，根据该地区，牛分枝杆菌病例与结核分枝杆菌病例（2000-2006年）的平均百分比为0.34%至1.0%。在布宜诺斯艾利斯，非艾滋病毒感染者和艾滋病毒/艾滋病患者的感染率呈缓慢下降趋势。在大多数国家，适用于分离M.牛，有助于低估这个问题。已证实人类存在BTB，尽管其相关性似乎很低。牛奶的巴氏杀菌、乳制品的卫生控制以及屠宰场的肉类检查有助于保护人类健康。然而，在职业上通过空气接触结核病牛及其尸体仍然是该区域的一个感染源。(C)2007 Elsevier Ltd.保留AR权利。
The aim of this work was to obtain the best possible estimate of the relevance of bovine tuberculosis (BTB) in humans in Argentina, Brazil, Chile, Colombia, Costa Rica, Dominican Republic, Ecuador, Peru, Uruguay and Venezuela. Sources of information were a questionnaire filled by the participant laboratories, and a search of published literature (1970-2007). Only four of these countries reported bacteriologically confirmed cases of BTB in humans. Most of these were diagnosed in Argentina, where the mean percentage of Mycobacterium bovis cases in relation to those due to Mycobacterium tuberculosis (2000-2006) ranged from 0.34% to 1.0%, according to the region. A slowly decreasing trend was observed in non HIV as well as in HIV/AIDS patients in Buenos Aires. In most of these countries, the low coverage of culture methods, especially of those including pyruvate-containing media, appropriate to isolate M. bovis, contributes to an underestimate of the problem. It was confirmed that BTB in humans exists, even though its relevance seems to be low. Milk pasteurization, sanitary controls to dairy products, and meat inspection at slaughterhouses contribute to the protection of human health. However, occupational aerogenous exposure to TB cattle and their carcasses remains a source of infection in the region. (C) 2007 Elsevier Ltd. AR rights reserved.