The Lang lecture 1986. The enigma of primary open-angle glaucoma.
The Lang lecture 1986. The enigma of primary open-angle glaucoma.
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朗讲座 1986。原发性开角型青光眼之谜。
DOI：
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
R. Smith
中科院分区：
文献类型：
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作者：
R. Smith
一个帐户给出了Moorfields前瞻性手术与药物试验原发性开角型青光眼。对52名受试者进行了长达18年的眼压、视野百分比计算和视力测定，每隔3个月进行一次。50%的患者通过随机选择接受了手术，并试图确定手术病例和医疗病例的表现是否更好。即使在这一延长期后，视野和眼内压水平之间的相关性很小，结果似乎有利于手术在视野方面有一定好处的可能性，而药物治疗可能对视力更好：但在这两种情况下都没有令人信服的证据。最后的结论是，需要更多的研究，但在此期间，太频繁和太详细的开角型青光眼的监测是不是特别有益的病人。
An account is given of the Moorfields prospective surgical v medical trial in primary open angle glaucoma. The intra-ocular pressure, visual fields calculated on a percentage basis and the visual acuity were measured in 52 subjects at 3 monthly intervals for up to 18 years. Fifty per cent of the patients underwent surgery by random selection and an attempt was made to determine whether the surgical or the medical cases fared better. Even after this extended period little correlation between visual field and the level of intra-ocular pressure could be found. The results appeared to favour the possibility that surgery was of some benefit in terms of visual field whereas medical therapy was probably better for visual acuity: but in neither case was convincing proof obtained. The final conclusion was that more research is needed but in the meantime too frequent and too elaborate surveillance of open angle glaucoma is not particularly beneficial to the patients.