Demographic and clinical features of neuromyelitis optica: A review.
Demographic and clinical features of neuromyelitis optica: A review.
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DOI：
10.1177/1352458515572406
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发表时间：
2015-06
期刊：
影响因子：
--
通讯作者：
GJCF International Clinical Consortium & Biorepository for Neuromyelitis Optica
中科院分区：
文献类型：
--
作者：
Pandit L;Asgari N;Apiwattanakul M;Palace J;Paul F;Leite MI;Kleiter I;Chitnis T;GJCF International Clinical Consortium & Biorepository for Neuromyelitis Optica
视神经肌萎缩症（NMO）的比较临床和人口统计学特征还不清楚。在这篇综述中，我们分析了同行评议的出版物的发病率和患病率，临床表型和人口统计学特征的NMO。来自欧洲、东南亚和南亚、加勒比和古巴的基于人群的研究表明，NMO的发病率和患病率分别为每10万人0.05-0.4和0.52-4.4。平均发病年龄（32.6-45.7岁）和首次复发的中位时间（8-12个月）相似。大多数研究报告了妇女的疾病过多和复发过程，特别是在抗水通道蛋白4抗体（抗AQP 4-IgG）阳性患者中。种族可能对疾病表型和临床结果有影响。尽管审查过程存在固有的局限性，但不同人群中NMO的临床和人口统计学特征中指出的主题促进了对NMO的更全面的理解和解决策略。
The comparative clinical and demographic features of neuromyelitis optica (NMO) are not well known. In this review we analyzed peer-reviewed publications for incidence and prevalence, clinical phenotypes, and demographic features of NMO. Population-based studies from Europe, South East and Southern Asia, the Caribbean, and Cuba suggest that the incidence and prevalence of NMO ranges from 0.05–0.4 and 0.52–4.4 per 100,000, respectively. Mean age at onset (32.6–45.7) and median time to first relapse (8–12 months) was similar. Most studies reported an excess of disease in women and a relapsing course, particularly in anti-aquaporin 4 antibody (anti AQP4-IgG)-positive patients. Ethnicity may have a bearing on disease phenotype and clinical outcome. Despite limitations inherent to the review process, themes noted in clinical and demographic features of NMO among different populations promote a more global understanding of NMO and strategies to address it.
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影响因子：
6.4
作者：
Jarius, Sven;Wildemann, Brigitte
通讯作者：
Wildemann, Brigitte
影响因子：
2.6
作者：
Asgari N;Skejoe HP;Lillevang ST;Steenstrup T;Stenager E;Kyvik KO
通讯作者：
Kyvik KO
影响因子：
5.1
作者：
Cossburn, M.;Tackley, G.;Robertson, N.
通讯作者：
Robertson, N.
DOI：
10.1177/1352458514555785
发表时间：
2015-06
期刊：
Multiple sclerosis (Houndmills, Basingstoke, England)
影响因子：
--
作者：
Höftberger R;Sepulveda M;Armangue T;Blanco Y;Rostásy K;Calvo AC;Olascoaga J;Ramió-Torrentà L;Reindl M;Benito-León J;Casanova B;Arrambide G;Sabater L;Graus F;Dalmau J;Saiz A
通讯作者：
Saiz A
影响因子：
14.5
作者：
Kitley, Joanna;Leite, M. Isabel;Palace, Jacqueline
通讯作者：
Palace, Jacqueline