Epidemiology and control of trachoma: systematic review.
Epidemiology and control of trachoma: systematic review.
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DOI：
10.1111/j.1365-3156.2010.02521.x
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发表时间：
2010-06
期刊：
影响因子：
--
通讯作者：
Mabey DC
中科院分区：
文献类型：
--
作者：
Hu VH;Harding-Esch EM;Burton MJ;Bailey RL;Kadimpeul J;Mabey DC
沙眼是导致失明的最常见的传染病。沙眼衣原体A-C血清型反复感染会导致儿童结膜发炎，成年后会形成疤痕和失明。据估计，2002年至少有130万人因沙眼失明，目前有4000万人被认为患有活动性疾病，820万人患有倒睫。这种疾病主要在发展中国家的贫穷农村社区中发现，特别是在撒哈拉以南非洲。世界卫生组织通过多方面的方法促进沙眼的控制，包括手术、大规模分发抗生素、鼓励面部清洁和改善环境。这与过去20年活动性疾病患病率的显著下降有关，但仍有大量倒睫患者面临失明风险。
Trachoma is the commonest infectious cause of blindness. Recurrent episodes of infection with serovars A–C of Chlamydia trachomatis cause conjunctival inflammation in children who go on to develop scarring and blindness as adults. It was estimated that in 2002 at least 1.3 million people were blind from trachoma, and currently 40 million people are thought to have active disease and 8.2 million to have trichiasis. The disease is largely found in poor, rural communities in developing countries, particularly in sub-Saharan Africa. The WHO promotes trachoma control through a multifaceted approach involving surgery, mass antibiotic distribution, encouraging facial cleanliness and environmental improvements. This has been associated with significant reductions in the prevalence of active disease over the past 20 years, but there remain a large number of people with trichiasis who are at risk of blindness.
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DOI：
10.1016/0035-9203(91)90470-j
发表时间：
1991-11-01
影响因子：
2.2
作者：
BAILEY, R;DOWNES, B;MABEY, D
通讯作者：
MABEY, D
影响因子：
13.7
作者：
Alemayehu, W;Melese, M;Fantaye, D
通讯作者：
Fantaye, D
影响因子：
1.8
作者：
Astle, William F.;Wiafe, Boateng;Glassco, Colin B.
通讯作者：
Glassco, Colin B.
影响因子：
4.1
作者：
Burton, MJ;Kinteh, F;Bailey, RL
通讯作者：
Bailey, RL
影响因子：
3.8
作者：
Andreasen, Aura A.;Burton, Matthew J.;Bailey, Robin L.
通讯作者：
Bailey, Robin L.