Dental caries experience and use of prescription medications among people aged 60+ in South Australia.
Dental caries experience and use of prescription medications among people aged 60+ in South Australia.
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南澳大利亚 60 岁人群的龋齿经历和处方药使用情况。
DOI：
10.1111/j.1741-2358.1995.tb00139.x
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Spencer,AJ
中科院分区：
文献类型：
--
作者：
Thomson,WM;Slade,GD;Spencer,AJ
长期以来，药物治疗一直被认为是老年人龋齿的潜在危险因素，尽管流行病学研究报告了药物使用与龋齿经历之间不一致的联系。本文旨在描述南澳大利亚州60岁以上非住院老人的用药频率，并检验用药与龋齿经历之间的关系。采用横断面调查设计，从1650人中收集了有关处方药使用的访谈数据。对848人进行了口腔检查，以获得有关冠根手杖经验的信息。服用处方药的次数从0到17次不等，平均服用次数为1.8次(SD，1.9)。在年龄较大的受试者和女性中，这一比例更高。四类药物占所用药物的近四分之三；其中，心血管药物(包括利尿剂)占三类，止痛药是唯一的非心血管类药物。服用3种或3种以上处方药的受试者根拐杖指数(RCI，均值=14.43；P<；0.01)高于服用1种或2种处方药的受试者(均值=11.50)，以及不服用处方药的受试者(均值=12.02)。对特定药物类型的检查显示，服用抗抑郁药物和抗溃疡药物的人有显著更高的RCI值(P<；0.05)。药物使用和根面龋病经历之间只有适度的关联，这可能归因于药物的干燥性效应，或者与潜在的医疗条件非因果关联。
Medication has long been implicated as a potential risk factor for dental caries among elderly people, although epidemiological studies have reported inconsistent associations between medication usage and dental caries experience. This paper aimed to describe the frequency of medication usage, and to examine associations between medication usage and dental caries experience among non‐institutionalized persons aged 60+ years in South Australia. A cross‐sectional survey design was used to collect interview data about prescription medication usage from 1,650 people. Oral examinations were conducted among 848 people to obtain information about coronal and root canes experience. The number of prescribed medications taken ranged from 0 to 17, and the mean number taken was 1.8 (sd, 1.9). This was higher in older subjects and females. Four medication categories accounted for almost three‐quarters of the medications taken; of those, cardiovascular drugs (including diuretics) accounted for three, with analgesics the only non‐cardiovascular class. Subjects taking 3 or more prescription medications had a higher Root Canes Index (RCI, mean = 14.43;P<0.01) than those taking one or two (mean = 11.50), and those who were taking none (mean = 12.02). Examination of particular medication types revealed that people who took antidepressants and antiulcer drugs had significantly higher RCI values (P<0.05). There was only a moderate association between medication usage and root caries experience which may be attributable to xerogenic effects of medication, or non‐causal associations with underlying medical conditions.
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