The duration of untreated psychosis among U.S. Latinxs and social and clinical correlates.

The duration of untreated psychosis among U.S. Latinxs and social and clinical correlates.
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DOI:
10.3389/fpsyt.2023.1052454
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发表时间:
2023
影响因子:
4.7
通讯作者:
Lopez, Steven Regeser
Lopez, Steven Regeser
中科院分区:
医学3区
文献类型:
--
作者:
Santos, Maria M. M.;Kratzer, Maya;Zavala, Jaqueline;Lopez, Daisy;Ullman, Jodie;Kopelowicz, Alex;Lopez, Steven Regeser

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本研究(a)记录了未治疗精神病(DUP)的持续时间,(b)在美国拉丁裔首发精神病(FEP)样本中检查了DUP的社会和临床相关性。收集的数据用于一项纵向研究,评估社区教育活动,以帮助主要讲西班牙语的拉丁人认识精神病症状并减少DUP,或在精神病症状发作后延迟首次开处方抗精神病药物。在首次治疗时评估社会和临床变量。使用DUP进行顺序层次回归,以确定DUP的独立预测因子。采用结构方程模型探讨DUP预测因子、DUP与临床和社会相关因素之间的关系。在122例具有FEP的拉丁患者中,中位DUP为39周(M = 137.78, SD = 220.31; IQR = 160.39-5.57)。对于整个样本来说,作为一个移民,自我报告的英语水平相对较差和自我报告的西班牙语水平较强,与精神病发作后较长时间延迟首次服药有关。对于移民亚组来说,移民时年龄越大,延迟时间越长。自我报告的英语水平成为民主统一党选举的独立预测指标。虽然DUP与症状无关,但它与较差的社会功能有关。通过DUP,自我报告的低英语能力与较差的社会功能有关。英语语言能力有限的拉丁裔人尤其有可能经历长时间的护理延误和社交功能低下。减少拉丁裔社区延误的干预措施应特别注意这一群体。
This study (a) documents the duration of untreated psychosis (DUP) and (b) examines both social and clinical correlates of DUP in a sample of U.S. Latinxs with first-episode psychosis (FEP). Data were collected for a longitudinal study evaluating a community education campaign to help primarily Spanish-speaking Latinxs recognize psychotic symptoms and reduce the DUP, or the delay to first prescribed antipsychotic medication after the onset of psychotic symptoms. Social and clinical variables were assessed at first treatment presentation. A sequential hierarchical regression was conducted using √DUP to identify independent predictors of the DUP. A structural equation model was used to explore the association between DUP predictors, DUP, and clinical and social correlates. In a sample of 122 Latinxs with FEP, the median DUP was 39 weeks (M = 137.78, SD = 220.31; IQR = 160.39–5.57). For the full sample, being an immigrant and having self-reported relatively poor English-speaking proficiency and self-reported strong Spanish-speaking proficiency were related to a longer delay to first prescribed medication after psychosis onset. For the immigrant subgroup, being older at the time of migration was related to a longer delay. Self-reported English-speaking proficiency emerged as an independent predictor of the DUP. Although the DUP was not related to symptomatology, it was associated with poorer social functioning. Low self-reported English-speaking ability is associated with poorer social functioning via the DUP. Latinxs with limited English language skills are especially at high risk for experiencing prolonged delays to care and poor social functioning. Intervention efforts to reduce the delay in Latinx communities should pay particular attention to this subgroup.
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