Monoclonal antibody 14F7, which recognizes a stage‐specific immature oligodendrocyte surface molecule, inhibits oligodendrocyte differentiation mediated in co‐culture with astrocytes
Monoclonal antibody 14F7, which recognizes a stage‐specific immature oligodendrocyte surface molecule, inhibits oligodendrocyte differentiation mediated in co‐culture with astrocytes
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单克隆抗体 14F7 可识别阶段特异性未成熟少突胶质细胞表面分子，抑制与星形胶质细胞共培养中介导的少突胶质细胞分化
DOI：
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发表时间：
1998
影响因子：
4.2
通讯作者：
H. Asou
中科院分区：
文献类型：
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作者：
K. Yoshimura;Y. Sakurai;D. Nishimura;Y. Tsuruo;Masayuki Nomura;S. Kawato;C. Seiwa;Taisen Iguchi;K. Itoh;H. Asou
处于少突胶质细胞谱系中间阶段的细胞不仅通过生化研究得到很好的表征，而且可能与生理事件的结果有关。为了阐明导致少突胶质细胞谱系细胞发育的分子事件，我们已经提出了针对阶段特异性未成熟少突胶质细胞的单克隆抗体，其先前已经通过新的少突胶质细胞谱系细胞培养技术分离（Sakurai等人：J Neurosci Res 52：17-26，1998）。
Cells at an intermediate stage of oligodendrocyte lineage are not only well characterized by biochemical studies but also are likely to relate to the outcome of physiological events. To elucidate the molecular events leading to the development of oligodendrocyte lineage cells, we have raised monoclonal antibodies against stage‐specific immature oligodendrocytes, which have previously been isolated by a novel oligodendrocyte‐lineage cell culture technique (Sakurai et al.: J Neurosci Res 52:17–26, 1998).
髓磷脂：从电绝缘体到离子通道。
DOI：
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发表时间：
1990
期刊：
Progress in clinical and biological research
影响因子：
--
作者：
Morell,P;Roberson,MD;Meissner,G;Toews,AD
通讯作者：
Toews,AD