THE MICROTUBULE LATTICE - 20 YEARS ON
THE MICROTUBULE LATTICE - 20 YEARS ON
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DOI：
10.1016/s0962-8924(00)88938-2
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发表时间：
1995-02-01
影响因子：
19
通讯作者：
AMOS, LA
中科院分区：
文献类型：
--
作者：
AMOS, LA
In 1974, optical diffraction and image analysis indicated that tubulin dimers in the cylindrically complete A-tubule of flagellar doublet microtubules are arranged with helical symmetry, while those in the incomplete B-tubule associate differently. Recently, electron micrographs of reassembled brain microtubules decorated with kinesin heads have shown that the tubulin dimers there are arranged as in the B-tubule. The lack of symmetry of microtubules assembled in vitro prompts Linda Amos to speculate here that the assembly process in vitro may differ from that occurring in the cell.
