THE TOPOGRAPHIC ORGANIZATION OF ASSOCIATIONAL FIBERS OF THE OLFACTORY SYSTEM IN THE RAT, INCLUDING CENTRIFUGAL FIBERS TO THE OLFACTORY-BULB
THE TOPOGRAPHIC ORGANIZATION OF ASSOCIATIONAL FIBERS OF THE OLFACTORY SYSTEM IN THE RAT, INCLUDING CENTRIFUGAL FIBERS TO THE OLFACTORY-BULB
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DOI：
10.1002/cne.902160305
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发表时间：
1983-01-01
影响因子：
2.5
通讯作者：
PRICE, JL
中科院分区：
文献类型：
--
作者：
LUSKIN, MB;PRICE, JL
本文用放射自显影方法对大鼠嗅皮质内的联合纤维进行了解剖学分析。在嗅皮层的所有分区中注入少量的3 H-亮氨酸，以选择性地标记每个区域中出现的纤维。在除嗅结节外的所有嗅皮质区均识别出皮质内纤维，并根据其层状终止模式将其分为2个主要系统（Ib层系统和II层-深Ib系统）（Luskin和Price，1983）。Ib层纤维系统起源于前嗅核、梨状皮质和外侧内嗅区，并与外侧嗅束相关。外侧嗅束深处或附近的皮质区域优先与嗅束附近的区域相互连接，而外侧嗅束外侧和尾部的皮质部分与嗅束外侧、尾部和内侧的区域相互连接最多。前嗅核和前梨状皮质的连合投射与同侧Ib层纤维系统的部分（但不是全部）成分相匹配。第Ⅱ层-深Ib纤维系统起源于腹侧被盖带、背脚皮质和杏仁核周围皮质3个小区域。腹侧带覆盖纤维终止于前嗅核的第二层，并在地形上组织。来自背脚皮质和杏仁周皮质的纤维分布较广，尤其是在皮质的外侧部和尾部。另外两个皮质内投影不适合这些纤维系统。外侧嗅束核向两侧投射到Calleja岛和梨状前皮质内侧缘。前皮质核投射到嗅皮质的许多部分，但纤维终止于I层（Ia和Ib层）的浅表和深部。有从几个嗅觉皮层区域到嗅觉皮层周围的皮层区域的投射。几乎所有的嗅觉区也投射到梨状皮质深处的腹侧和背侧梨状核和/或嗅结节深处的多形区。杏仁核的深核，特别是从更腹内侧和尾部的嗅觉皮质的投射被证明。
This study analyzed the topographic organization of the associational fibers within the olfactory cortex of the rat by using the autoradiographic method. Small injections of 3H-leucine were placed in all of the subdivisions of the olfactory cortex to label selectively the fibers arising in each area. Intracortical fibers were identified from all of the olfactory cortical areas except the olfactory tubercle, and were classified into 2 major systems (the layer Ib system and the layer II-deep Ib system) on the basis of their laminar pattern of termination (Luskin and Price, 1983). The layer Ib fiber system arises in the anterior olfactory nucleus, piriform cortex and lateral entorhinal area, and is broadly organized in relation to the lateral olfactory tract. Cortical areas deep to or near the lateral olfactory tract are preferentially interconnected with areas near the tract, while parts of the cortex lateral and caudal to the lateral olfactory tract are most heavily interconnected with areas lateral, caudal and medial to the tract. Commissural projections from the anterior olfactory nucelus and the anterior piriform cortex match some (but not all) components of the ipsilateral layer Ib fiber system. The layer II-deep Ib fiber system arises in 3 small areas.sbd.the ventral tenia tecta, the dorsal peduncular cortex and the periamygdaloid cortex. The fibers from the ventral tenia tecta terminate in layer II of the anterior olfactory nucleus and are topographically organized. The fibers from the dorsal peduncular cortex and the periamygdaloid cortex are more widely distributed, especially in the lateral and caudal parts of the cortex. Two other intracortical projections do not fit into either of these fiber systems. The nucleus of the lateral olfactory tract projects bilaterally to the islands of Calleja and the medial edge of the anterior piriform cortex. The anterior cortical nucleus projects to many parts of the olfactory cortex, but the fibers end in both superficial and deep parts of layer I (layer Ia and Ib). There are projections from several of the olfactory cortical areas to the cortical areas surrounding the olfactory cortex. Virtually all of the olfactory areas also project to the ventral and dorsal endopiriform nuclei deep to the piriform cortex and/or to the polymorph zone deep to the olfactory tubercle. Projections were demonstrated to the deep amygdaloid nuclei, especially from the more ventromedial and caudal parts of the olfactory cortex.