Relationship between metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
Relationship between metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema
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DOI：
10.1007/s00417-016-3382-2
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发表时间：
2016-11-01
影响因子：
2.7
通讯作者：
Oshika, Tetsuro
中科院分区：
文献类型：
--
作者：
Murakami, Tomoya;Okamoto, Fumiki;Oshika, Tetsuro
目的探讨视网膜分支静脉阻塞所致黄斑囊样水肿(BRVO-CME)患者黄斑中心凹微结构与光谱域光学相干断层扫描(SD-OCT)测量结果之间的关系。我们使用M图检查视力和视物变形的严重程度。用SD-OCT软件测量中心凹厚度、中心凹视网膜中央厚度(CRT-1 mm)和黄斑体积。对椭圆区(EZ)、外界膜(ELM)、视网膜外囊肿、视网膜内囊肿的情况进行了评估，平均视力变形评分为0.77+/-0.50，其中28例(93%)有视力变形(视力变形评分为0.2)。垂直变形视力评分(0.89±-0.54)显著高于水平变形视力评分(0.64+/-0.53)(p<；0.005)。EZ和ELM的状态与视力显著相关，但与平均视力变形评分无关。视力变形评分与CRT-1 mm(p<；0.05)和视网膜内囊的存在(p<；0.05)显著相关，视变形的严重程度与视网膜中央厚度和视网膜内囊的存在显著相关。
We aimed to investigate the relationship between the severity of metamorphopsia and the foveal microstructure measured with spectral-domain optical coherence tomography (SD-OCT) in patients with cystoid macular edema caused by branch retinal vein occlusion (BRVO-CME).The study included 30 eyes of 30 patients with BRVO-CME. We examined visual acuity and the severity of metamorphopsia using M-CHARTS. Central foveal thickness, central retinal thickness at the fovea (CRT-1 mm), and macular volume were measured with SD-OCT software. The status of ellipsoid zone (EZ), external limiting membrane (ELM), outer retinal cyst, and inner retinal cyst was also evaluated.The mean metamorphopsia score was 0.77 +/- 0.50, with 28 of 30 patients (93 %) having metamorphopsia (metamorphopsia score aeyen 0.2). The vertical metamorphopsia score (0.89 +/- 0.54) was significantly higher than the horizontal metamorphopsia score (0.64 +/- 0.53) (p < 0.005). The status of EZ and ELM was significantly associated with visual acuity, but not with the mean metamorphopsia score. The mean metamorphopsia score was significantly related to CRT-1 mm (p < 0.05) and the presence of inner retinal cyst (p < 0.05).The severity of metamorphopsia was significantly associated with central retinal thickness and the presence of inner retinal cyst.