Regional brain cerebral glucose metabolism and temperament: A positron emission tomography study

Regional brain cerebral glucose metabolism and temperament: A positron emission tomography study
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DOI:
10.1016/j.neulet.2005.11.017
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发表时间:
2006-03-20
影响因子:
2.5
通讯作者:
Inada, T
Inada, T
中科院分区:
医学4区
文献类型:
--
作者:
Hakamata, Y;Iwase, M;Inada, T

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个性,特别是气质,被认为有生物学基础。本研究探讨了脑局部葡萄糖代谢与气质的关系。应用[F-18]氟脱氧葡萄糖正电子发射断层扫描技术对31名健康受试者的局部脑葡萄糖代谢进行了测定。使用气质和性格量表评估气质。气质维度被观察到与特定的大脑区域显着相关。特别是,新奇寻求与上级颞回、顶叶下小叶和楔前叶显着相关,据报道这些区域与冲动有关,而奖励依赖与尾状核显着相关,已被证明与奖励处理有关。气质的各个方面可能在特定的大脑区域有生物学基础。这类研究结果的积累应该会提供更多的证据,将人格特征与其生物学基础联系起来。(c)2005爱思唯尔爱尔兰有限公司保留所有权利。
Personality, and in particular temperament, is thought to have a biological basis. In the present study, the relationships between regional brain glucose metabolism and temperament have been investigated. Regional brain glucose metabolism was measured using [F-18] fluorodeoxyglucose positron emission tomography in 31 healthy subjects. Temperament was assessed using the Temperament and Character Inventory. Temperament dimensions were observed to be significantly correlated with specific brain regions. In particular, novelty seeking was significantly correlated with the superior temporal gyrus, inferior parietal lobule, and the precuneus, which have been reported to be related with impulsiveness, while reward dependence was significantly correlated with the caudate head, which has been shown to be associated with reward processing. The various aspects of temperament may have biological bases in the specific brain regions. The accumulation of results from studies of this kind should provide further evidence connecting personality traits with their biological bases. (c) 2005 Elsevier Ireland Ltd. All rights reserved.