Screening performance of K6/K10 and other screening instruments for mood and anxiety disorders in Japan
Screening performance of K6/K10 and other screening instruments for mood and anxiety disorders in Japan
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DOI：
10.1111/j.1440-1819.2011.02236.x
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发表时间：
2011-01-01
影响因子：
11.9
通讯作者：
Kawakami, Norito
中科院分区：
文献类型：
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作者：
Sakurai, Keiko;Nishi, Akihiro;Kawakami, Norito
目的：建立日本版Kessler(K)6、K10和抑郁与自杀筛查(DSS)的筛查性能和最佳临界点。方法：随机抽取日本社区居民(非病例，n=147)和根据DSM-IV诊断为心境或焦虑障碍的精神科门诊患者(n=17)，采用K6、K10、DSS和流行病学研究中心抑郁量表(CES-D)组成的自填式问卷进行调查。绘制受试者-操作者特征(ROC)曲线，以K6、K10和DSS的最佳截断点估计曲线下面积(AUC)、灵敏度和特异度，并与CES-D进行比较。结果：K6和K10具有较高的AUC(0.93-0.94)，与CES-D(0.95)相当，但DSS的AUC(0.89)明显小于CES-D(P<；0.05)。K6、K10和DSS的最佳分界点分别为4/5、9/10和1/2。这三种量表的敏感性相似，但DSS的特异性低于其他两种量表。K6、K10和DSS被评为“非常容易”或“好用”的程度显著高于CES-D(P<；0.01)。结论：日文版K6和K10的筛选性能与CES-D相当，优于DDS。K6/K10，特别是K6，可能具有优势，甚至比CES-D更有优势，因为它的筛选性能相似，可接受性更好。
Aims: This study aimed to establish the screening performance and optimal cut-off points for the Japanese version of Kessler (K) 6, K10 and the Depression and Suicide Screen (DSS).Methods: A self-report questionnaire including K6, K10 and DSS, as well as the Center for Epidemiologic Studies - Depression Scale (CES-D), was administered to a random sample of community residents in Japan (non-cases, n = 147) and psychiatric outpatients diagnosed with mood or anxiety disorders according to DSM-IV (cases, n = 17). A receiver-operator characteristics (ROC) curve was drawn to estimate the area under the curve (AUC), the sensitivity, and specificity with the optimal cut-off points for K6, K10, and DSS, which were then compared with those of CES-D. The community sample was also asked to rate each measure on a scale from 'very easy' to 'very hard' to use.Results: K6 and K10 showed a high AUC (0.93-0.94), which was comparable to that of CES-D(0.95), but DSS showed a significantly smaller AUC (0.89) than CES-D (P < 0.05). The optimal cut-off points were estimated as 4/5 for K6, 9/10 for K10, and 1/2 for DSS. The sensitivity of these three scales was similar, but the specificity was lower for DSS than for the other two. K6, K10 and DSS were rated as being 'very easy' or 'easy to use' significantly more than CES-D (P < 0.01).Conclusion: The screening performance of the Japanese versions of K6 and K10 was comparable with that of CES-D, and better than that of DDS. K6/K10, particularly K6, might have an advantage, even over the CES-D, because of its similar screening performance and better acceptability.