Enhancing Efficacy of a Brief Obesity and Eating Disorder Prevention Program: Long-Term Results from an Experimental Therapeutics Trial.

Enhancing Efficacy of a Brief Obesity and Eating Disorder Prevention Program: Long-Term Results from an Experimental Therapeutics Trial.
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DOI:
10.3390/nu15041008
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发表时间:
2023-02-17
期刊:
影响因子:
5.9
通讯作者:
Shaw H
Shaw H
中科院分区:
医学2区
文献类型:
--
作者:
Stice E;Rohde P;Butryn ML;Desjardins C;Shaw H

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目的:测试健康项目(一项肥胖/饮食失调预防计划)的有效性是否通过在单一性别群体中实施并增加食物反应抑制和注意力训练而得到改善。方法:高风险年轻人(N = 261; M年龄= 19.3,74%女性)被随机分配到(1)单性别或(2)混合性别组,完成食物反应抑制和注意力训练,或(3)单性别或(4)混合性别组,完成非食物图像的假训练。结果如下:训练类型与训练时间的交互作用存在显著的性别构成;完成单一性别或混合性别健康项目组加上食物反应和注意力训练的参与者在2年的随访中显示出体脂的显著减少,尽管这种效果在单一性别组中更迅速和持久,而那些完成单一或混合性别健康项目组加假训练的人没有显示出体脂变化。然而,在随访期间,超重/肥胖发作没有差异。操纵因素并不影响进食障碍症状或进食障碍发作,但在所有条件下症状都显著减少(条件内d =-0.58),与之前的证据相一致,即健康项目比教育对照参与者产生了更大的症状减少(条件内d =-0.48)。2年随访期间的平均进食障碍发作率(6.4%)与过去一项试验中在健康项目中观察到的结果(4.5%)相似。结论:鉴于健康项目在先前的试验中显着减少了未来超重/肥胖的发生,并且本试验发现,在单一性别组中实施并与食物反应和注意力训练配对时,体脂减少效果显着更大,因此广泛实施这种联合干预可能有价值。
Objective: Test whether the efficacy of Project Health, an obesity/eating disorder prevention program, is improved by delivering it in single-sex groups and adding food response inhibition and attention training. Method: High-risk young adults (N = 261; M age = 19.3, 74% female) were randomized to (1) single-sex or (2) mixed-sex groups that completed food response inhibition and attention training or (3) single-sex or (4) mixed-sex groups that completed sham training with nonfood images in a 2 × 2 factorial design. Results: There was a significant sex-composition by training-type by time interaction; participants who completed single- or mixed-sex Project Health groups plus food response and attention training showed significant reductions in body fat over a 2-year follow-up, though this effect was more rapid and persistent in single-sex groups, whereas those who completed single- or mixed-sex Project Health groups plus sham training did not show body fat change. However, there were no differences in overweight/obesity onset over the follow-up. The manipulated factors did not affect eating disorder symptoms or eating disorder onset, but there was a significant reduction in symptoms across the conditions (within-condition d = −0.58), converging with prior evidence that Project Health produced larger reductions in symptoms (within-condition d = −0.48) than educational control participants. Average eating disorder onset over the 2-year follow-up (6.4%) was similar to that observed in Project Health in a past trial (4.5%). Conclusions: Given that Project Health significantly reduced future onset of overweight/obesity in a prior trial and the present trial found that body fat loss effects were significantly greater when implemented in single-sex groups and paired with food response and attention training, there might be value in broadly implementing this combined intervention.