Genotoxicity of organic pollutants in source of drinking water on microalga Euglena gracilis

Genotoxicity of organic pollutants in source of drinking water on microalga Euglena gracilis
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饮用水源中有机污染物对微藻Euglena gracilis的遗传毒性

DOI:
10.1007/s10646-009-0343-0
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发表时间:
2009-08-01
期刊:
影响因子:
2.7
通讯作者:
Cui, Yibin
Cui, Yibin
中科院分区:
环境科学与生态学4区
文献类型:
--
作者:
Li, Mei;Hu, Changwei;Cui, Yibin

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采用彗星试验和抗氧化酶法研究了太湖梅梁湾饮用水源地中有机污染物对纤细裸藻的潜在毒性。水样有机提取物对微藻细胞有DNA损伤作用。0.3x、3x和10x浓度组与对照组和溶剂对照组(DMSO)相比,差异有统计学意义(P<0.05)。有机提取物还影响微藻的抗氧化酶活性和诱导脂质过氧化。高剂量组超氧化物歧化酶含量明显升高(P<0.05)。结果表明,水样提取液中的浓缩有机物对细毛藻有一定的毒害作用,可能会对生态系统造成破坏。
The potential toxicities of organic pollutants in the drinking water source at Meiliang Bay of Lake Taihu were investigated by comet assay and antioxidant enzyme approach on microalgae Euglena gracilis. The organic extracts of the water samples could induce DNA damage on microalgae cells. Statistically significant differences (P < 0.05) were observed at groups of 0.3x, 3x and 10x concentrations compared with the control and a solvent control (DMSO). The organic extracts also affected antioxidant enzyme activity and induced lipid peroxidation in the microalga. In the high dose group, there was an obvious increase in SOD content (P < 0.05). The results suggest that the concentrated organics from water sample extracts have adversary effects on E. gracilis and could possibly damage the ecosystem.