The relation between blood osmotic pressure, fluid distribution and voluntary water intake

The relation between blood osmotic pressure, fluid distribution and voluntary water intake
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DOI:
10.1152/ajplegacy.1937.120.2.323
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发表时间:
1937-10-01
影响因子:
--
通讯作者:
Gilman, A
Gilman, A
中科院分区:
其他
文献类型:
--
作者:
Gilman, A

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在注射后,狗的自愿摄水量有明显的不同。高渗溶液。等渗氯化钠(20%)和尿素(40%),尽管血液渗透压有相同的升高。在给予高渗氯化钠后,动物立即消耗了足够的水来稀释它们的血液到前驱。在尿素后,在没有同等口渴刺激的情况下,水的摄入量较少,血液渗透压保持较高水平。这种水分摄入量的差异归因于细胞内水分含量的不同。
Voluntary water intake in dogs differed markedly following the inj. of hypertonic solns. of isosmolar NaCl (20%) and urea (40%) despite identical increases in blood osmotic pressure. After the administration of hypertonic NaCl animals immediately consumed sufficient water to dilute their blood to the preinj. level; after urea, in the absence of an equal thirst stimulus, water intake was less and the osmotic pressure of the blood remained elevated. This difference in water intake was attributed to the difference of the water content in the cell.