Electrodeposition of cell-laden alginate-PLL hydrogel structures for spatially selective entrapment
Electrodeposition of cell-laden alginate-PLL hydrogel structures for spatially selective entrapment
复制标题
电沉积载有细胞的藻酸盐-PLL水凝胶结构用于空间选择性捕获
DOI：
10.1109/iros.2015.7353547
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Qiang Huang
中科院分区：
文献类型：
--
作者：
Zeyang Liu;Masaru Takeuchi;M. Nakajima;T. Fukuda;Y. Hasegawa;Qiang Huang
本研究利用电沉积法制备了任意形状的藻酸盐-聚赖氨酸（PLL）水凝胶。在含有碳酸钙颗粒的海藻酸钠溶液中电解水，可诱导海藻酸钠在微图案化阳极电极上凝胶化，并形成载有细胞的海藻酸钠凝胶结构。几种不同形状的凝胶通过预定义的微图案一次生成。通过在掺氟氧化锡（FTO）载玻片上涂覆光刻胶制备微图案化电极。将藻酸盐-PLL包封技术引入该平台，形成藻酸盐-PLL水凝胶结构。该方法为组织工程支架材料的制备提供了更准确、更有创造性的方法。
In this study, cell-laden alginate-poly-L-lysine (PLL) hydrogel structures with arbitrary shapes were constructed based on electrodeposition method. Electrolysis of water in alginate solutions with calcium carbonate particles induced alginate gelation on micro-patterned anode electrode, and cell-laden alginate gel structures were formed. The several different shapes of gel were generated at one time by predefined micro-patterns. The micro-patterned electrode was fabricated by coating photoresist on Fluorine-doped tin oxide (FTO) glass slide. Alginate-PLL encapsulation technique was introduced to this platform forming alginate-PLL hydrogel structures. This proposed method can lead to more accurate and creative studies of fabricating cell-laden scaffold for tissue engineering.
影响因子：
6.1
作者：
Sugiura, Shinji;Oda, Tatsuya;Nakajima, Mitsutoshi
通讯作者：
Nakajima, Mitsutoshi