Is the Effect of Body Mass Index on Hypertension Modified by the Elevation? A Cross-Sectional Study of Rural Areas in Japan.

Is the Effect of Body Mass Index on Hypertension Modified by the Elevation? A Cross-Sectional Study of Rural Areas in Japan.
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DOI:
10.3390/ijerph14091022
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发表时间:
2017-09-07
影响因子:
--
通讯作者:
Nabika T
Nabika T
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Hamano T;Shiotani Y;Takeda M;Abe T;Sundquist K;Nabika T

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肥胖是发生高血压的既定独立危险因素。最近的一项研究表明,肥胖对高血压的影响因居住地区海拔的不同而不同。因此,我们假设体重指数(BMI)和海拔的交互作用与高血压有显着相关性。这项横断面研究的首要目的是在调整协变量后检查 BMI 是否与高血压相关。第二个目的是在调整协变量后检查 BMI 和海拔之间的相互作用项是否与高血压相关。数据收集自 2016 年在日本农村地区进行的一项横断面研究。排除缺失数据的参与者 (n = 2) 后,对 729 名参与者的数据进行了分析。我们发现BMI与高血压显着相关。此外,BMI和海拔之间的交互项与高血压有显着相关性。本研究的结果支持了最近的证据,即高 BMI 是高血压的独立危险因素,但其影响因海拔高度而异。因此,针对具体情况的干预措施可能是预防该领域高血压的有效方法。
Obesity is an established independent risk factor for developing hypertension. A recent study showed that the effect of obesity on hypertension varies by the elevation of the residence area. Thus, we hypothesized that the interaction effect of body mass index (BMI) and elevation has a significant association with hypertension. The first aim of this cross-sectional study was to examine whether BMI was associated with hypertension, after adjustment for covariates. The second aim was to examine whether the interaction term between BMI and elevation was associated with hypertension, after adjustment for covariates. Data were collected from a cross-sectional study conducted in a rural area of Japan in 2016. After excluding participants with missing data (n = 2), data from 729 participants were analyzed. We found that BMI was significantly associated with hypertension. In addition, the interaction term between BMI and elevation had a significant association with hypertension. The findings of the present study support the recent evidence that high BMI is an independent risk factor for hypertension, but its effect varies by elevation. Thus, context-specific interventions could be an effective approach to prevent hypertension in this area.
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