Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
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DOI:
10.1083/jcb.201907013
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发表时间:
2020-01
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影响因子:
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通讯作者:
Reika Tei;Jeremy M. Baskin
中科院分区:
文献类型:
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作者:
Reika Tei;Jeremy M. Baskin
Tei et al. developed optogenetic phospholipase D enzymes for precisely generating the pleiotropic lipid second-messenger phosphatidic acid on specific organelle membranes and applied these tools to elucidate that a PM pool of phosphatidic acid can attenuate Hippo signaling.