Monoclonal antibodies to anchoring fibrils for the diagnosis of epidermolysis bullosa.

Monoclonal antibodies to anchoring fibrils for the diagnosis of epidermolysis bullosa.
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锚定原纤维的单克隆抗体用于诊断大疱性表皮松解症。

DOI:
10.1111/1523-1747.ep12522669
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发表时间:
1983
期刊:
The Journal of investigative dermatology
影响因子:
--
通讯作者:
Briggaman,RA
Briggaman,RA
中科院分区:
--
文献类型:
--
作者:
Goldsmith,LA;Briggaman,RA

文献摘要

被引文献

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鼠抗人锚定纤维的单抗与人和猴子的宫颈、舌头、食道和阴道反应。大鼠、小鼠和豚鼠组织均为阴性。11例营养不良性隐性大疱性表皮松解症患者免疫荧光和免疫电子显微镜检查均未见反应。其他类型的大疱性表皮松解症反应正常。
Murine monoclonal antibodies to human anchoring fibrils reacted with human and monkey cervix, tongue, esophagus, and vagina. Rat, mouse, and guinea pig tissues were negative. In 11 patients with dystrophic recessive epidermolysis bullosa there was no reaction by immunofluorescence and immunoelectron microscopy. Other forms of epidermolysis bullosa had normal reactivity.