Retrospective motion correction protocol for high-resolution anatomical MRI

Retrospective motion correction protocol for high-resolution anatomical MRI
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DOI:
10.1002/hbm.20235
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发表时间:
2006-12-01
影响因子:
4.8
通讯作者:
Fox, Peter
Fox, Peter
中科院分区:
医学2区
文献类型:
--
作者:
Kochunov, Peter;Lancaster, Jack L.;Fox, Peter

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现代计算脑形态学方法要求以高分辨率和高信噪比采集解剖图像。这通常意味着采集时间较长(> 20分钟),图像易受头部运动的影响。在这项研究中,我们测试了回顾性运动校正(RMC),常见的功能磁共振成像(fMRI)和PET图像运动校正,作为一种手段,以提高高分辨率的3-D解剖MR图像的质量。已知RMC方法可有效校正扫描间运动;因此,将单个高分辨率3-D MRI脑部研究分为6个较短的采集段,以帮助将扫描内运动转换为扫描间运动。为了帮助减少扫描内头部运动,对每个节段图像进行运动伪影审查,并在必要时重复。通过将图像空间配准到第三图像并形成单个平均运动校正图像来进行扫描间运动校正。在35名被认为具有头部运动高风险的受试者中进行了RMC测试。我们的研究结果表明,RMC提供了更好的对比度噪声比和边界细节相比,nonmotion-corrected平均图像。
Modern computational brain morphology methods require that anatomical images be acquired at high resolution and with a high signal-to-noise ratio. This often translates into long acquisition times (> 20 minutes) and images susceptible to head motion. In this study we tested retrospective motion correction (RMC), common for functional MRI (fMRI) and PET image motion correction, as a means to improve the quality of high-resolution 3-D anatomical MR images. RMC methods are known to be effective for correcting interscan motion; therefore, a single high-resolution 3-D MRI brain study was divided into six shorter acquisition segments to help shift intrascan motion into interscan motion. To help reduce intrascan head motion, each segment image was reviewed for motion artifacts and repeated if necessary. Interscan motion correction was done by spatially registering images to the third image and forming a single average motion-corrected image. RMC was tested on 35 subjects who were considered at high risk for head motion. Our results show that RMC provided better contrast-to-noise ratio and boundary detail when compared to nonmotion-corrected averaged images.