Efficacy of Exposure Therapy for Japanese Patients With Posttraumatic Stress Disorder Due to Mixed Traumatic Events: A Randomized Controlled Study

Efficacy of Exposure Therapy for Japanese Patients With Posttraumatic Stress Disorder Due to Mixed Traumatic Events: A Randomized Controlled Study
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DOI:
10.1002/jts.20589
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发表时间:
2010-12-01
影响因子:
3.3
通讯作者:
Nishikawa, Toru
Nishikawa, Toru
中科院分区:
医学3区
文献类型:
--
作者:
Asukai, Nozomu;Saito, Azusa;Nishikawa, Toru

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作者研究了长期暴露(PE)疗法对患有创伤后应激障碍(PTSD)的日本患者的疗效。 24 名因混合创伤而患有 PTSD 的患者(21 名女性,3 名男性)被随机分配到 PE 组(PE 接受或不接受常规治疗 [TAU])或仅对照组 (TAU)。对照组在 10 周后接受 PE 治疗。意向治疗分析显示,治疗后,PE 组的 PTSD 或抑郁症状比对照组显着减少。对照组在 PE 治疗后症状严重程度显着降低。在 12 个月的随访评估中,两组 19 名 PE 完成者的症状水平仍然较低。该研究的结果将促进未来在非西方环境中传播和实施针对创伤后应激障碍的循证治疗。
The authors examined the efficacy of Prolonged Exposure (PE) therapy in Japanese patients with posttraumatic stress disorder (PTSD). Twenty-four patients (21 women, 3 men) with PTSD due to mixed trauma were randomly assigned to the PE group (PE with or without treatment as usual [TAU]) or the control group (TAU) only. The control group received PE after a 10-week period. Intention-to-treat analysis showed the PE group achieved significantly greater reduction than the control group at posttreatment in either PTSD or depressive symptoms. The control group had significantly decreased symptom severity after PE treatment. Symptom levels of 19 PE completers in the both groups remained low in 12-month follow-up assessments. The study's findings will promote the future dissemination and implementation of evidence-based treatment for PTSD in non-Western settings.