The effects of chronic treadmill and wheel running on behavior in rats
The effects of chronic treadmill and wheel running on behavior in rats
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DOI：
10.1016/j.brainres.2004.05.086
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发表时间：
2004-09-03
期刊：
影响因子：
2.9
通讯作者：
Wilson, MA
中科院分区：
文献类型：
--
作者：
Burghardt, PR;Fulk, LJ;Wilson, MA
为了更好地理解体育锻炼引起的行为适应，本实验在一系列行为测试中评估了两种跑步运动模式的效果。研究了8周强制跑步和自愿轮式跑步对高架加迷宫、开阔场地、社会互动和条件冻结范式行为测量的影响。在任何测试范式中，八周的跑步机跑步都没有改变行为。在高架迷宫中，给予不受限制的跑轮（WR）的大鼠与锁轮控制（LC）（20.7 +/- 5.7%）相比，打开ann时间的百分比较低（6.0 +/- 2.3%）。与对照组相比，WR也显示出较少的进入中心（0.2 +/- 0.2）和较少的交叉（61.0 +/- 14.9）。WR组和LC组的社会互动均有所增加；然而，这些差异归因于住房条件。我们还研究了4周的轮毂跑对高架迷宫和开阔场地行为的影响，以解决运动对行为的时间效应的可能性。四周的滚轮跑在开阔地带产生的行为变化与8周时的相似，但在高强度的迷宫中却没有，这表明滚轮跑对迷宫行为有时间影响。在4周和8周的转轮运动后发现的行为适应不仅仅是由于丰富的环境，而且似乎表明增强的防御行为。(C) 2004 Elsevier B.V.版权所有
In order to better understand the behavioral adaptations induced by physical activity, this set of experiments assessed the effects of two modes of running exercise on a battery of behavioral tests. The effects of 8 weeks of forced treadmill running and voluntary wheel running on behavior measures in the elevated plus maze, open field, social interaction and conditioned freezing paradigms were investigated. Eight weeks of treadmill running did not alter behavior in any test paradigm. Rats given unrestricted access to running wheels (WR) had a lower percent open ann time (6.0 +/- 2.3%) compared to locked wheel controls (LC) (20.7 +/- 5.7%) in the elevated plus maze. WR also showed decreased entries into center (0.2 +/- 0.2) and crossed fewer lines (61.0 +/- 14.9) in the open field compared to control groups. Both WR and LC groups showed increased social interaction; however, these differences are attributed to housing conditions. The effects of 4 weeks of wheel running on elevated plus maze and open field behavior were also investigated to address the possibility of a temporal effect of exercise on behavior. Four weeks of wheel running produced behavioral changes in the open field similar to those found at 8 weeks, but not in the elevated plus maze suggesting a temporal effect of wheel running on plus maze behavior. The behavioral adaptations found after 4 and 8 weeks of wheel running were not due solely to enriched environment and appear to be indicative of enhanced defensive behavior. (C) 2004 Elsevier B.V. All rights reserved.