Characterizing the epidemiology, virology, and clinical features of influenza in China's first severe acute respiratory infection sentinel surveillance system, February 2011-October 2013
Characterizing the epidemiology, virology, and clinical features of influenza in China's first severe acute respiratory infection sentinel surveillance system, February 2011-October 2013
复制标题
DOI：
10.1186/s12879-015-0884-1
复制
发表时间：
2015-03-22
影响因子：
3.7
通讯作者：
Yu, Hongjie
中科院分区：
文献类型：
--
作者：
Peng, Zhibin;Feng, Luzhao;Yu, Hongjie
背景：2009年甲型H1N1流感pdm09大流行后，中国首次建立了严重急性呼吸道感染（SARI）哨点监测系统。方法：我们分析了2011年2月至2013年10月中国10个省10家医院的SARI病例资料。结果：在5644例急性呼吸道感染病例中，330例（6%）为流感阳性。其中，62%为甲型流感，38%为乙型流感。与流感阴性病例相比，流感阳性SARI病例的中位年龄更高（20.0岁对11.0岁，p = 0.003），并且更有可能患有至少一种潜在的慢性疾病（年龄调整百分比：28%对25%，p < 0.001）。sars监测发现的优势毒株类型/亚型几乎总是在流感样疾病（ILI）监测系统发现的优势毒株中，并且两个系统的流感活动同时达到高峰。结论：来自中国首个严重急性呼吸道感染哨点监测系统的数据表明，严重急性呼吸道感染病例中流行流感毒株的类型/亚型和流行趋势与ILI病例相似。
Background: After the 2009 influenza A(H1N1) pdm09 pandemic, China established its first severe acute respiratory infections (SARI) sentinel surveillance system.Methods: We analyzed data from SARI cases in 10 hospitals in 10 provinces in China from February 2011 to October 2013.Results: Among 5,644 SARI cases, 330 (6%) were influenza-positive. Among these, 62% were influenza A and 38% were influenza B. Compared with influenza-negative cases, influenza-positive SARI cases had a higher median age (20.0 years vs. 11.0, p = 0.003) and were more likely to have at least one underlying chronic medical condition (age adjusted percent: 28% vs. 25%, p < 0.001). The types/subtypes of dominant strains identified by SARI surveillance was almost always among dominant strains identified by the influenza like illness (ILI) surveillance system and influenza activity in both systems peaked at the same time.Conclusions: Data from China's first SARI sentinel surveillance system suggest that types/subtypes of circulating influenza strains and epidemic trends among SARI cases were similar to those among ILI cases.