The carbohydrate-protein linkage region of chondroitin 6-sulfate.
The carbohydrate-protein linkage region of chondroitin 6-sulfate.
复制标题
6-硫酸软骨素的碳水化合物-蛋白质连接区域。
DOI:
10.1016/0304-4165(68)90010-x
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发表时间:
1968
期刊:
影响因子:
--
通讯作者:
L. Rodén
中科院分区:
文献类型:
--
作者:
T. Helting;L. Rodén
The structure of the chondroitin 6-sulfate-protein linkage region has been investigated. Chondroitin 6-sulfate was prepared from umbilical cord by digestion with papain followed by fractionation with cetylpyridinium chloride and ethanol. Four oligosaccharides derived from the linkage region were isolated after acid hydrolysis of the polysaccharide and characterized as:(1) 3-O-β-D-glucuronosyl-D-galactose;(2) 3-O-β-D-galactosyl-D-galactose;(3) 4-O-β-D-galactosyl-D-xylose; and (4) 3-O-β-D-galactosyl-4-O-β-D-galactosyl-D-xylose. It is concluded that the carbohydrate sequence in the chondroitin 6-sulfate-protein linkage is identical to that previously found for chondroitin 4-sulfate and heparin.